3-(四氢-2H-吡喃-2-基氧基)丙烷-1-醇合成路线 （共 11 条）
反应条件
in dichloromethane T=0 - 20°C; 3 h; Inert atmosphere;
参考文献
Ayala, Caitlan E.; Villalpando, Andres; Nguyen, Alex L.; McCandless, Gregory T.; Kartika, Rendy
Organic Letters, 2012 , vol. 14, # 14 p. 3676 - 3679
反应条件
aluminium trichloride; silica gel in 1,2-dichloro-ethane
T=20°C; 1.8 h;
参考文献
Borujeni, Kaveh Parvanak
Synthetic Communications, 2006 , vol. 36, # 18 p. 2705 - 2710
反应条件
toluene-4-sulfonic acid
Etherification;
参考文献
Ramaseshan, Mahesh; Robitaille, Martin; Ellingboe, John W.; Dory, Yves L.; Deslongchamps, Pierre
Tetrahedron Letters, 2000 , vol. 41, # 24 p. 4737 - 4742
反应条件
Ti-HMS; hydrogen; 5 percent palladium-carbon in methanol
P=760 Torr; 4 h; Ambient temperature;
参考文献
Itoh, Akichika; Kodama, Tomohiro; Maeda, Shiro; Masaki, Yukio
Tetrahedron Letters, 1998 , vol. 39, # 51 p. 9461 - 9464
反应条件
hydrogenchloride in dichloromethane; water
T=25°C; Title compound not separated from byproducts;
参考文献
Petroski, Richard J.
Synthetic Communications, 2003 , vol. 33, # 18 p. 3251 - 3259
反应条件
Dowex 50W x 2 in toluene
T=30°C; Etherification; hydration; 3.66667 h;
参考文献
Nishiguchi, Takeshi; Fujisaki, Shizuo; Kuroda, Masahumi; Kajisaki, Kohtaro; Saitoh, Masahiko
Journal of Organic Chemistry, 1998 , vol. 63, # 23 p. 8183 - 8187
反应条件
1: 56 percent / NH2OH*HCl; aq. EtNH2; CuCl / methanol / 0 °C
2: 55 percent / HF*pyridine; AcOH / tetrahydrofuran
3: 94 percent / K2CO3 / methanol / 4 h
View Scheme
参考文献
Gung, Benjamin W.; Fox, Ryan M.
Tetrahedron, 2004 , vol. 60, # 42 p. 9405 - 9415
反应条件
copper diacetate; oxygen; magnesium
1.) THF, 25 deg C, 1h; 2.) CH3OH, NH4OH,; Multistep reaction. Title compound not separated from byproducts;
参考文献
Keana, John F. W.; Seyedrezai, Seyed E.; Gaughan, Glen
Journal of Organic Chemistry, 1983 , vol. 48, # 16 p. 2644 - 2647
参考文献
Ramaseshan, Mahesh; Robitaille, Martin; Ellingboe, John W.; Dory, Yves L.; Deslongchamps, Pierre
Tetrahedron Letters, 2000 , vol. 41, # 24 p. 4737 - 4742
反应条件
dipyridinium dichromate; magnesium sulfate in dichloromethane
T=25°C; 48 h; Title compound not separated from byproducts;
参考文献
Petroski, Richard J.
Synthetic Communications, 2003 , vol. 33, # 18 p. 3243 - 3250
