2,3-二溴-4-氧-2-丁烯酸合成路线 （共 43 条）
参考文献
Jackson; Hill
Chemische Berichte, 1878 , vol. 11, p. 1673
American Chemical Journal, 1881 , vol. 3, p. 111
反应条件
carbon disulfide; phosphorus; iodine anschliessend Behandeln mit Wasser;
参考文献
Hill; Cornelison
American Chemical Journal, 1894 , vol. 16, p. 208
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
T=-10 - -5°C; 1.66667 h;
参考文献
Blazecka, Peter Garth; Zhang, Ji
Patent: US2005/59831 A1, 2005 ;
Location in patent: Page/Page column 7 ;
参考文献
Limpricht
Justus Liebigs Annalen der Chemie, 1873 , vol. 165, p. 279
参考文献
Schmelz; Beilstein
Justus Liebigs Annalen der Chemie, 1864 , vol. Suppl.3, p. 275
参考文献
Schmelz; Beilstein
Justus Liebigs Annalen der Chemie, 1864 , vol. Suppl.3, p. 275
Full Text Show Details
Jackson; Hill
Chemische Berichte, 1878 , vol. 11, p. 289
American Chemical Journal, 1881 , vol. 3, p. 106
反应条件
1: 2,2-dimethylpropaneimidamide hydrochloride With sodium ethanolate in ethanol
T=50°C;
2: 2,3-dibromomalealdehydic acid in ethanol
T=55°C;
3: With hydrogenchloride; sodium ethanolate
more than 3 stages;
参考文献
Carter, Percy H.; Cherney, Robert J.; Batt, Douglas G.; Duncia, John V.; Gardner, Daniel S.; Ko, Soo S.; Srivastava, Anurag S.; Yang, Michael G.
Patent: US2005/54627 A1, 2005 ;
Location in patent: Page/Page column 38 ;
US 20050054627 A1
反应条件
1: 2,2-dimethylpropaneimidamide hydrochloride With sodium ethanolate in ethanol
2: 2,3-dibromomalealdehydic acid in ethanol
T=50 - 55°C;
3: With hydrogenchloride; sodium ethanolate
more than 3 stages;
参考文献
Carter, Percy H.; Cherney, Robert J.; Batt, Douglas G.; Brown, Gregory D.; Duncia, John V.; Gardner, Daniel S.; Yang, Michael G.
Patent: US2005/54626 A1, 2005 ;
Location in patent: Page/Page column 35 ;
US 20050054626 A1
反应条件
sodium nitrite in ethanol; water
T=0 - 60°C;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; WASHBURN, William N.; MURUGAIAH SUBBAIAH, Murugaiah Andappan; AHMAD, Saleem
Patent: WO2014/39412 A1, 2014 ;
Location in patent: Paragraph 00232 ;
参考文献
Schmelz; Beilstein
Justus Liebigs Annalen der Chemie, 1864 , vol. Suppl.3, p. 275
Full Text Show Details
Jackson; Hill
Chemische Berichte, 1878 , vol. 11, p. 289
American Chemical Journal, 1881 , vol. 3, p. 106
