2,3-二溴-4-氧-2-丁烯酸合成路线

Gong, Yong; Barbay, J. Kent; Dyatkin, Alexey B.; Miskowski, Tamara A.; Kimball, Edward S.; Prouty, Stephen M.; Fisher, M. Carolyn; Santulli, Rosemary J.; Schneider, Craig R.; Wallace, Nathaniel H.; Ballentine, Scott A.; Hageman, William E.; Masucci, John A.; Maryanoff, Bruce E.; Damiano, Bruce P.; Andrade-Gordon, Patricia; Hlasta, Dennis J.; Hornby, Pamela J.; He, Wei
Journal of Medicinal Chemistry, 2006 , vol. 49, # 11 p. 3402 - 3411

21577-50-42,3-二溴-4-氧-2-丁烯酸+

20570-96-1苄基肼二盐酸盐

134965-39-22-苄基-4,5-二溴吡嗪-3(2H)-酮

参考文献

MERCK FROSST CANADA and CO.
Patent: EP975604 B1, 2004 ;
Location in patent: Page 40 ;

21577-50-42,3-二溴-4-氧-2-丁烯酸

16900-53-1

参考文献

Jackson; Hill
Chemische Berichte, 1878 , vol. 11, p. 1673
American Chemical Journal, 1881 , vol. 3, p. 111