1-(2-硫代-2,3-二氢-1H-苯并咪唑-1-基)乙酮合成路线 (共 7 条)
反应条件
1: 73 percent / Et3N / tetrahydrofuran / 8 h / Ambient temperature 2: KOH / acetone / 0.17 h 3: acetic acid / methanol / 0.5 h / Heating View Scheme
参考文献
Braun, Stephan; Botzki, Alexander; Salmen, Sunnhild; Textor, Christian; Bernhardt, Guenther; Dove, Stefan; Buschauer, Armin
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4419 - 4429
反应条件
acetic acid in methanol 0.5 h; Heating; Yield given;
参考文献
Doerge; Cooray
Synthetic Communications, 1991 , vol. 21, # 17 p. 1789 - 1795
反应条件
1: KOH / acetone / 0.17 h 2: acetic acid / methanol / 0.5 h / Heating View Scheme
参考文献
Doerge; Cooray
Synthetic Communications, 1991 , vol. 21, # 17 p. 1789 - 1795
反应条件
hydrogenchloride in ethanol; water controlled potential electrolysis; pH=2;
参考文献
Fahmy, Hussein M.; Daboun, Hamed A.; Azziz, Kamal; Azzem, M. Abdel
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , p. 425 - 432
参考文献
Braun, Stephan; Botzki, Alexander; Salmen, Sunnhild; Textor, Christian; Bernhardt, Guenther; Dove, Stefan; Buschauer, Armin
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4419 - 4429
参考文献
Vasan, Mahalakshmi; Neres, Joao; Williams, Jessica; Wilson, Daniel J.; Teitelbaum, Aaron M.; Remmel, Rory P.; Aldrich, Courtney C.
ChemMedChem, 2010 , vol. 5, # 12 p. 2079 - 2087
反应条件
pyridine Ambient temperaturestand overnight;
参考文献
Saxena, D. B.; Khajuria, R. K.; Suri, O. P.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 681 - 683