N-[(5-溴-2-噻吩基)甲基]氨基甲酸叔丁酯合成路线 (共 5 条)
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide T=0 - 20°C; Darkness;
参考文献
Klare, Jennifer E.; Murray, Ian P.; Goldberger, Joshua; Stupp, Samuel I.
Chemical Communications, 2009 , # 25 p. 3705 - 3707
反应条件
1: triethylamine / dichloromethane / 4 h 2: N-bromosuccinmide / N,N-dimethyl-formamide / 18 h / Darkness View Scheme
参考文献
Journal of Polymer Science, Part A: Polymer Chemistry, , vol. 49, # 22 p. 4861 - 4874
反应条件
1: triethylamine / dichloromethane / 4 h 2: N-bromosuccinmide / N,N-dimethyl-formamide / 18 h / Darkness View Scheme
参考文献
Journal of Polymer Science, Part A: Polymer Chemistry, , vol. 49, # 22 p. 4861 - 4874
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 2 h;
参考文献
Klare, Jennifer E.; Murray, Ian P.; Goldberger, Joshua; Stupp, Samuel I.
Chemical Communications, 2009 , # 25 p. 3705 - 3707
反应条件
hydrogenchloride in ethyl acetate 2 h;
参考文献
SUNESIS PHARMACEUTICALS; BIOGEN IDEC, INC.
Patent: WO2008/5457 A2, 2008 ;
Location in patent: Page/Page column 185 ;
WO 2008/005457 A2