2-叔丁基-异吲哚-1,3-二酮合成路线 (共 27 条)
反应条件
1: 78 percent / 0.25 h / Ambient temperature
2: 85 percent / Et3N / acetonitrile / 0.17 h
View Scheme
参考文献
Kehler, Jan; Breuer, Eli
Synthesis, 1998 , # 10 p. 1419 - 1420
反应条件
1: 1.) PyBOP, (i-Pr)2NEt / 1.) THF, r.t., 40 min, 2.) r.t., 30 min
2: 67 percent / p-TsOH / toluene / 4 h / Heating
View Scheme
参考文献
Aguilar, Nuria; Moyano, Albert; Pericas, Miquel A.; Riera, Antoni
Synthesis, 1998 , # 3 p. 313 - 316
反应条件
1: 51 percent / CHCl3 / 3 h / Ambient temperature
2: 81 percent / CrO3, aq. H2SO4 / acetone / 1 h / Ambient temperature
View Scheme
参考文献
Nishio, Takehiko; Yamamoto, Hiroshi
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 883 - 892
反应条件
1: dichloromethane / 20 °C / |Inert atmosphere
2: triethylamine / dichloromethane / 23 - 25 °C / |Inert atmosphere
View Scheme
参考文献
Goodman, Cassie A.; Hamaker, Christopher G.; Hitchcock, Shawn R.
Tetrahedron Letters, 2013 , vol. 54, # 45 p. 6012 - 6014
反应条件
Ambient temperature;
参考文献
Bouzobaa, M.; Leclerc, G.
Tetrahedron Letters, 1984 , vol. 25, # 29 p. 3067 - 3070
参考文献
Smith; Emerson
Org. Synth. Coll. Vol. III. <1955>151
反应条件
zinc in acetic acid
4 h; Heating;
参考文献
Kreher, Richard P.; Hennige, Hans; Jelitto, Frank; Preut, Johannes
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1989 , vol. 44, # 9 p. 1132 - 1148