4-羟基-1-苯基吡唑并[3,4-D]嘧啶合成路线 （共 29 条）
反应条件
sodium ethanolate in ethanol P=15001.5 Torr; 0.0125 h; RefluxMicrowave irradiation; TimePressure;
参考文献
Devarakonda, Murty; Doonaboina, Raghava; Vanga, Sreedher; Vemu, Jahnavi; Boni, Sathoshini; Mailavaram, Raghu Prasad
Medicinal Chemistry Research, 2013 , vol. 22, # 3 p. 1090 - 1101
反应条件
[BsMIm][HSO4] T=80°C; 0.0333333 h; neat (no solvent);
参考文献
Tavakoli-Hoseini, Niloofar; Moloudi, Raheleh; Davoodnia, Abolghasem; Shaker, Mohammad
Chinese Journal of Chemistry, 2011 , vol. 29, # 11 p. 2421 - 2426
反应条件
sodium ethanolate in ethanol 14 h; Heating;
参考文献
Miyashita, Akira; Iijima, Chihoko; Higashino, Takeo; Matsuda, Hideaki
Heterocycles, 1990 , vol. 31, # 7 p. 1309 - 1314
反应条件
sulfuric acid T=90°C; 0.5 h;
参考文献
Klemm, Kurt; Pruesse, Wolfgang; Baron, Lothar; Daltrozzo, Ewald
Chemische Berichte, 1981 , vol. 114, # 6 p. 2001 - 2018
反应条件
n-Pentyl nitrite; toluene-4-sulfonic acid in chlorobenzene Heating; Yields of byproduct given;
参考文献
Press, Jeffery B.; Eudy, Nancy H.; Morton, George O.
Journal of Organic Chemistry, 1983 , vol. 48, # 24 p. 4605 - 4611
反应条件
T=190°C; 4 h; Neat (no solvent)Inert atmosphere;
参考文献
Ho, Jonathan Z.; Van Arsdale, Kyle R.; Braun, Matthew P.
Helvetica Chimica Acta, 2008 , vol. 91, # 5 p. 958 - 963
反应条件
n-Pentyl nitrite; toluene-4-sulfonic acid 72 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 48, # 24 p. 4605 - 4611
反应条件
1: 66 percent / 2 M NaOH / 0.5 h / Heating 2: 11 percent / dimethylformamide / 12 h / Ambient temperature View Scheme
参考文献
Australian Journal of Chemistry, , vol. 44, # 7 p. 1001 - 1005
反应条件
in N,N-dimethyl-formamide 6 h; Heating;
参考文献
Nagahara; Kawano; Sasaoka; Ukawa; Hirama; Takada; Cottam; Robins
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 1 p. 239 - 243
反应条件
1: ethanol / 4 h / Heating 2: H2O / 24 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 9 p. 2121 - 2125
