5-甲基-2-巯基苯并噻唑合成路线 （共 8 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20 - 150°C; 16 h;
参考文献
HYDRA BIOSCIENCES, INC.
Patent: WO2006/122156 A2, 2006 ;
Location in patent: Page/Page column 126 ;
WO 2006/122156 A2
反应条件
carbon disulfide; hydrogen sulfide
参考文献
Nippon Soda Company Limited
Patent: US3967951 A1, 1976 ;
反应条件
in N,N-dimethyl-formamide
参考文献
Tularik Inc.
Patent: US2003/139390 A1, 2003 ;
US 20030139390 A1
参考文献
Zeneca Limited
Patent: US5451594 A1, 1995 ;
反应条件
phosphorus pentachloride
参考文献
I.G. Farbenind.
Patent: DE516998 , 1928 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 611
Full Text Show Details
I.G. Farbenind.
Patent: US1878699 , 1929 ;
反应条件
ammonium hydrogen sulfite; ammonium hydroxide T=150°C;
参考文献
Ubaldini; Fiorenza
Gazzetta Chimica Italiana, 1946 , vol. 76, p. 215,221
反应条件
iron in acetic acid Heating;
参考文献
Taddei,F. et al.
Gazzetta Chimica Italiana, 1965 , vol. 95, p. 499 - 506
反应条件
1: 65 percent / aq. NaOH / 3 h / Ambient temperature
2: 97 percent / NH2NH2*H2O, EtOH / 5 h / 80 °C
View Scheme
参考文献
Easmon; Heinisch; Hofmann; Langer; Grunicke; Fink; Puerstinger
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 5 p. 397 - 408
