4-甲基-3,4-二氢-2H-1,4-苯并噁嗪-2-羧酸合成路线 （共 3 条）
反应条件
potassium hydroxide in tetrahydrofuran; methanol T=20°C; 1 h;
参考文献
Touzeau, Frederique; Arrault, Axelle; Guillaumet, Gerald; Scalbert, Elizabeth; Pfeiffer, Bruno; Rettori, Marie-Claire; Renard, Pierre; Merour, Jean-Yves
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1962 - 1979
反应条件
1: 67 percent / K2CO3 / acetone / 18 h / Heating 2: 93 percent / aq. KOH / methanol; tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 10 p. 1962 - 1979
反应条件
1: 68 percent / K2CO3 / acetone / 20 h / Heating 2: 67 percent / K2CO3 / acetone / 18 h / Heating 3: 93 percent / aq. KOH / methanol; tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 10 p. 1962 - 1979
