1,3-二甲基-2,5-吡咯烷二酮合成路线 （共 3 条）
反应条件
1: With triethylamine in dichloromethane T=0 - 20°C; 2: With 1,1'-carbonyldiimidazole in dichloromethane T=20°C; 2 h; Heating / reflux;
参考文献
BAYER HEALTHCARE AG
Patent: WO2004/113290 A1, 2004 ;
Location in patent: Page/Page column 31 ;
WO 2004/113290 A1
反应条件
1,1'-carbonyldiimidazole in dichloromethane T=0 - 45°C;
参考文献
Pohlmann, Jens; Lampe, Thomas; Shimada, Mitsuyuki; Nell, Peter G.; Pernerstorfer, Josef; Svenstrup, Niels; Brunner, Nina A.; Schiffer, Guido; Freiberg, Christoph
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1189 - 1192
反应条件
1: acetyl chloride / 60 °C 2: N,N'-carbonyldiimidazole / CH2Cl2 / 0 - 45 °C View Scheme
参考文献
Pohlmann, Jens; Lampe, Thomas; Shimada, Mitsuyuki; Nell, Peter G.; Pernerstorfer, Josef; Svenstrup, Niels; Brunner, Nina A.; Schiffer, Guido; Freiberg, Christoph
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1189 - 1192
