N-(2-苯基苯基)乙酰胺合成路线 （共 68 条）
反应条件
1: (chlorination) 2: (i) aq. HCl, EtOH, (ii) NaNO2, (iii) KI 3: (i) Mg, Et2O, (ii) /BRN= 1900390/, MeI View Scheme
参考文献
Fuson,R.C.; Talbott,R.L.
Journal of Organic Chemistry, 1961 , vol. 26, p. 2674 - 2676
反应条件
palladium diacetate; copper diacetate; 3 A molecular sieve; oxygen in toluene T=120°C; 12 h;
参考文献
Tsang, W. C. Peter; Zheng, Nan; Buchwald, Stephen L.
Journal of the American Chemical Society, 2005 , vol. 127, # 42 p. 14560 - 14561
反应条件
1: glacial acetic acid; bromine 2: alcoholic hydrobromic acid / Hydrolysis View Scheme
参考文献
Scarborough; Waters
Journal of the Chemical Society, 1927 , p. 94
反应条件
1: chlorine 2: aqueous hydrochloric acid 3: Diazotization.Umsetzung mit CuCl View Scheme
参考文献
de Crauw
Recueil des Travaux Chimiques des Pays-Bas, 1931 , vol. 50, p. 753,779
反应条件
oxygen; copper diacetate; palladium dichloride in N,N-dimethyl acetamide T=140°C; P=760.051 Torr; 48 h;
参考文献
Liu, Yan-Yun; Song, Ren-Jie; Wu, Cui-Yan; Gong, Lu-Bin; Hu, Ming; Wang, Zhi-Qiang; Xie, Ye-Xiang; Li, Jin-Heng
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 2-3 p. 347 - 353
反应条件
hydrogenchloride; potassium iodide; mercury(II) iodide; sodium nitrite Yield given. Multistep reaction;
参考文献
Cornforth, John; Ridley, Damon D.; Sierakowski, Andrew F.; Uguen, Daniel; Wallace, Timothy W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 10 p. 2317 - 2332
反应条件
silver fluoride; copper(II) bis(trifluoromethanesulfonate); palladium diacetate in 1,4-dioxane
T=110°C; 36 h;
参考文献
Yang, Shangdong; Li, Bijie; Wan, Xiaobing; Shi, Zhangjie
Journal of the American Chemical Society, 2007 , vol. 129, # 19 p. 6066 - 6067
反应条件
silver fluoride; copper(II) bis(trifluoromethanesulfonate); palladium diacetate in 1,4-dioxane
T=110°C; 48 h;
参考文献
Yang, Shangdong; Li, Bijie; Wan, Xiaobing; Shi, Zhangjie
Journal of the American Chemical Society, 2007 , vol. 129, # 19 p. 6066 - 6067
参考文献
GENENTECH, INC.
Patent: WO2008/134679 A1, 2008 ;
Location in patent: Page/Page column 84 ;
反应条件
silver fluoride; copper(II) bis(trifluoromethanesulfonate); palladium diacetate in 1,4-dioxane
T=110°C; 48 h;
参考文献
Yang, Shangdong; Li, Bijie; Wan, Xiaobing; Shi, Zhangjie
Journal of the American Chemical Society, 2007 , vol. 129, # 19 p. 6066 - 6067
