1-(2-氟苯基)-1-丙酮合成路线 (共 36 条)
反应条件
CsSO4F
1 h; Ambient temperature; Further byproducts given. Title compound not separated from byproducts;
参考文献
Stavber, Stojan; Zupan, Marko
Journal of Organic Chemistry, 1987 , vol. 52, # 22 p. 5022 - 5025
反应条件
ammonium hydroxide; fluorine
1.) MeOH/MeCN, -40 deg C; Yield given. Multistep reaction;
参考文献
Kamaya, Hiroshi; Sato, Masayuki; Kaneko, Chikara
Tetrahedron Letters, 1997 , vol. 38, # 4 p. 587 - 590
反应条件
sodium hexamethyldisilazane
1.) THF, -78 deg C, 2.) 20 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Davis, Franklin A.; Han, Wei
Tetrahedron Letters, 1991 , vol. 32, # 13 p. 1631 - 1634
反应条件
hydrogenchloride; sodium carbonate; N-fluorobislt;(trifluoromethyl)sulfonylgt;imide
1.) CH2Cl2, room temp., 5 h, 2.) CH2Cl2; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ying; DesMarteau; Gotoh
Tetrahedron, 1996 , vol. 52, # 1 p. 15 - 22
反应条件
N-fluorosaccharin; lithium hexamethyldisilazane
multistep reaction: selectivity mono:difluorination; other bases, other carbonyl compounds; Product distribution;
参考文献
Differding, Edmond; Rueegg, Gabriela M.; Lang, Robert W.
Tetrahedron Letters, 1991 , vol. 32, # 15 p. 1779 - 1782
反应条件
chlorine in N,N-dimethyl-formamide
T=100°C; 0.5 h;
参考文献
Kimpe, Norbert De; Verhe, Roland; Buyck, Laurent De; Schamp, Niceas
Journal of Organic Chemistry, 1980 , vol. 45, # 14 p. 2803 - 2813