1: acetonitrile / 48 h 2: 1.) lithium diisopopylamide / 1) THF, room temperature, 1 h; 2) THF, room temperature, 2 h 3: 129 mg / pyridine / 1) -20 deg C, 30 min; 2) 4 deg C, 2 h 4: 77 mg / NaI / acetone / 3 h / Heating 5: dimethylsulfoxide / 40 °C 6: aq. NaOH / methanol; H2O / 22 h View Scheme

1: 1.) lithium diisopopylamide / 1) THF, room temperature, 1 h; 2) THF, room temperature, 2 h 2: 129 mg / pyridine / 1) -20 deg C, 30 min; 2) 4 deg C, 2 h 3: 77 mg / NaI / acetone / 3 h / Heating 4: dimethylsulfoxide / 40 °C 5: aq. NaOH / methanol; H2O / 22 h View Scheme

1: 129 mg / pyridine / 1) -20 deg C, 30 min; 2) 4 deg C, 2 h 2: 77 mg / NaI / acetone / 3 h / Heating 3: dimethylsulfoxide / 40 °C 4: aq. NaOH / methanol; H2O / 22 h View Scheme

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