乙酰溴-Alpha-D-葡萄糖酮酸甲基酯合成路线 （共 53 条）
反应条件
1: benzene; silver oxide 2: aq. NaOH solution View Scheme
参考文献
Huebner et al.
Journal of Biological Chemistry, 1944 , vol. 155, p. 615
参考文献
Salvatella, Mariona; Arsequell, Gemma; Valencia, Gregorio; Rodriguez, Raquel E.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 4 p. 905 - 908
反应条件
1: 85 percent / Ag2CO3 / benzene / 72 h / Ambient temperature 2: NaBH4 / PdCl2 / methanol / 0.5 h / 0 °C 3: hydrolysis View Scheme
参考文献
Numazawa, Mitsuteru; Nagaoka, Masao; Tsuji, Masachika; Osawa, Yoshio
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 1 p. 121 - 125
反应条件
1: methanol / Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin View Scheme
参考文献
Helferich et al.
Chemische Berichte, 1956 , vol. 89, p. 2220,2221
反应条件
methanol; potassium ethanolate T=-78°C; Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin;
参考文献
Helferich et al.
Chemische Berichte, 1956 , vol. 89, p. 2220,2221
反应条件
1: 45 percent / benzyltriethylammonium chloride; aq. NaOH / CHCl3 / 5 h / Heating 2: NaOMe; MeOH / 1 h / 20 °C 3: 0.068 mmol / LiOH / tetrahydrofuran; H2O / 1 h / 20 °C View Scheme
参考文献
Park, Sungjin; Shin, Injae
Organic Letters, 2007 , vol. 9, # 4 p. 619 - 622
反应条件
sodium azide; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane; sodium hydrogencarbonate T=20°C; azidation; 2 h;
参考文献
Florio, Pas; Thomson, Robin J.; Von Itzstein, Mark
Carbohydrate Research, 2000 , vol. 328, # 4 p. 445 - 448
反应条件
Ag2CO3 in dichloromethane Ambient temperature;
参考文献
Saito, Setsuo; Sasaki, Yuka; Furumoto, Takako; Sumita, Shigeya; Hinomoto, Tohru
Carbohydrate Research, 1994 , vol. 258, p. 59 - 76
反应条件
1: caesium carbonate / acetonitrile / 3 h / 70 °C 2: hydrogenchloride / 1,4-dioxane / 76 h / 20 °C 3: morpholine; tetrakis(triphenylphosphine) palladium(0) / dichloromethane / 4 h / 20 °C View Scheme
参考文献
Uchiyama, Minoru; Fischer, Thomas; Mueller, Juergen; Oguchi, Minoru; Yamamura, Naotoshi; Koda, Hiroko; Iwabuchi, Haruo; Izumi, Takashi
Drug Metabolism and Disposition, 2010 , vol. 38, # 6 p. 946 - 956
反应条件
1: caesium carbonate / acetonitrile / 3 h / 70 °C 2: hydrogenchloride / 1,4-dioxane / 76 h / 20 °C 3: morpholine; tetrakis(triphenylphosphine) palladium(0) / dichloromethane / 4 h / 20 °C 4: water; acetonitrile 5: sodium acetate / water; acetonitrile / 296 h / 20 °C View Scheme
参考文献
Uchiyama, Minoru; Fischer, Thomas; Mueller, Juergen; Oguchi, Minoru; Yamamura, Naotoshi; Koda, Hiroko; Iwabuchi, Haruo; Izumi, Takashi
Drug Metabolism and Disposition, 2010 , vol. 38, # 6 p. 946 - 956
