5-环丙基异噁唑-3-甲酸乙酯合成路线 （共 3 条）
反应条件
1,4-diaza-bicyclo[2.2.2]octane in ethanol T=150°C; 0.333333 h; Microwave irradiation;
参考文献
KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN Randamp;;D; reMYND; GRIFFIOEN, Gerard; VAN DOOREN, Tom; ROJAS DE LA PARRA, Veronica; MARCHAND, Arnaud; ALLASIA, Sara; KILONDA, Amuri; CHALTIN, Patrick
Patent: WO2010/142801 A1, 2010 ;
Location in patent: Page/Page column 151 ;
WO 2010/142801 A1
反应条件
hydroxylamine hydrochloride in ethanol 1 h; Heating / reflux;
参考文献
Piotrowski, David W.; Rogers, Bruce N.; McWhorter JR., William W.; Walker, Daniel Patrick; Corbett, Jeffrey W.; Groppi JR., Vincent E.; Rudmann, Daniel G.
Patent: US2003/236287 A1, 2003 ;
Location in patent: Page 46, 47 ;
US 20030236287 A1
反应条件
1: With water; sodium hydroxide T=20°C; 72 h; 2: With hydrogenchloride in water pH=1;
参考文献
WO2010/142801 A1, ;
Page/Page column 151 ;
WO 2010/142801 A1
