5,7-二羟基-4-甲基香豆素合成路线 （共 25 条）
反应条件
aluminum oxide; methanesulfonic acid T=20°C; Pechmann reaction; 0.333333 h;
参考文献
Sharghi, Hashem; Jokar, Mahboubeh
Heterocycles, 2007 , vol. 71, # 12 p. 2721 - 2733
反应条件
acetoacetic acid methyl ester; polyaniline-sulfate salt catalyst powder (20 wt percent with respect to phenols) T=150°C; 6 h;
参考文献
Council of Scientific and Industrial Research
Patent: US6716996 B1, 2004 ;
Location in patent: Page column 8 ;
反应条件
scandium tris(trifluoromethanesulfonate) T=80°C; Pechmann condensation; 1 h;
参考文献
Parhami, Abolfath; Zare, Abdolkarim; Nikrooz, Marzieh; Khalafi-Nezhad, Ali; Haghighi, Saghar Mowlazadeh; Bargebid, Rahele; Moosavi-Zare, Ahmad Reza
ARKIVOC (Gainesville, FL, United States), 2012 , vol. 2012, # 9 p. 111 - 121,11
反应条件
zinc(II) chloride T=100°C; 0.0833333 h; neat (no solvent);
参考文献
Leao, Raquel A. C.; Def.demoraes, Paula; Pedro, Marcella C. B. C.; Costa, Paulo R. R.
Synthesis, 2011 , # 22 art. no. M70011SS, p. 3692 - 3696
反应条件
toluene-4-sulfonic acid in chlorobenzene T=60°C; von Pechmann reaction; 9 h;
参考文献
Hirai, Takeshi; Togo, Hideo
Synthesis, 2005 , # 16 art. no. F05605SS, p. 2664 - 2668
反应条件
1: 2,2,6-trimethyl-4H-1,3-dioxin-4-one With dihydroxy-poly(ethylene glycol) of MW = 4000 in toluene 5 h; Heating; 2: 1,3,5-trishydroxybenzene With titanium tetrachloride in tetrahydrofuran T=20°C; von Pechmann reaction; 0.666667 h;
参考文献
Sheng, Shou-Ri; Huang, Pei-Gang; Wang, Qiong; Huang, Ren; Liu, Xiao-Ling
Synthetic Communications, 2006 , vol. 36, # 21 p. 3175 - 3181
反应条件
titanium tetrachloride in ethanol T=20°C; Pechmann Condensation;
参考文献
Sharma, Aditi; Tiwari, Meena; Supuran, Claudiu T.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2014 , vol. 29, # 2 p. 292 - 296
反应条件
boron trifluoride T=60°C; Pechmann reaction; 0.0833333 h;
参考文献
Stoyanov, Edmont V.; Mezger, Jochen
Molecules, 2005 , vol. 10, # 3 p. 720 - 724
反应条件
sulfuric acid in ethyl acetate T=20°C; 12 h;
参考文献
Chemical Communications, , # 31 p. 3296 - 3298
