顺式-8,11,14-二十碳三烯酸甲酯合成路线 （共 9 条）
反应条件
1: With potassium hydroxide; water in methanol T=55°C; 1.5 h; 2: methanol With sulfuric acid in water T=20 - 55°C; 1.5 h; Product distribution / selectivity;
参考文献
WASHINGTON STATE UNIVERSITY
Patent: WO2008/86495 A1, 2008 ;
Location in patent: Page/Page column 18; 21-22; 29 ;
反应条件
1: CuI, NaI, K2CO3 / dimethylformamide / 5 h / 20 °C 2: K2CO3, methanol / 4.5 h / 20 °C 3: CBr4, PPh3 / CH2Cl2 / 0 °C 4: CuI, NaI, K2CO3 / dimethylformamide / 5 h / 20 °C 5: H2 / Lindlar catalyst, quinoline View Scheme
参考文献
Groza; Ivanov; Myagkova
Russian Journal of Bioorganic Chemistry, 1998 , vol. 24, # 6 p. 401 - 404
反应条件
1: CBr4, PPh3 / CH2Cl2 / 0 °C 2: CuI, NaI, K2CO3 / dimethylformamide / 5 h / 20 °C 3: H2 / Lindlar catalyst, quinoline View Scheme
参考文献
Groza; Ivanov; Myagkova
Russian Journal of Bioorganic Chemistry, 1998 , vol. 24, # 6 p. 401 - 404
反应条件
1: CuI, NaI, K2CO3 / dimethylformamide / 5 h / 20 °C 2: H2 / Lindlar catalyst, quinoline View Scheme
参考文献
Groza; Ivanov; Myagkova
Russian Journal of Bioorganic Chemistry, 1998 , vol. 24, # 6 p. 401 - 404
反应条件
hydrogen; quinoline; Lindlar's catalyst
参考文献
Groza; Ivanov; Myagkova
Russian Journal of Bioorganic Chemistry, 1998 , vol. 24, # 6 p. 401 - 404
反应条件
T=55°C; 1.5 h; Product distribution / selectivity;
参考文献
WASHINGTON STATE UNIVERSITY
Patent: WO2008/86495 A1, 2008 ;
Location in patent: Page/Page column 18; 21-22; 29 ;
反应条件
(i) (COCl)2, benzene, (ii) /BRN= 102415/, ether, (iii) AgOCOPh, Et3N; Multistep reaction;
参考文献
Struijk,C.B. et al.
Recueil des Travaux Chimiques des Pays-Bas, 1966 , vol. 85, p. 1233 - 1250
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Struijk,C.B. et al.
Recueil des Travaux Chimiques des Pays-Bas, 1966 , vol. 85, p. 1233 - 1250
反应条件
lithium hydroxide in methanol 2 h; Ambient temperature; Yield given;
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 24, # 6 p. 401 - 404
