吡啶并[2,3-D]嘧啶-2,4(1H,3H)-二酮合成路线 (共 20 条)
反应条件
1: POCl3 2: H2O; NaHS View Scheme
参考文献
Robins; Hitchings
Journal of the American Chemical Society, 1955 , vol. 77, p. 2256,2259
反应条件
trichlorophosphate 1 h; Heating;
参考文献
Sanmartin, Carmen; Echeverria, Mikel; Mendivil, Beatriz; Cordeu, Lucia; Cubedo, Elena; Garcia-Foncillas, Jesus; Font, Maria; Palop, Juan Antonio
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 6 p. 2031 - 2044
反应条件
sodium hydroxide in methanol; water 4 h; Heating;
参考文献
Reisch; Usifoh; Oluwadiya
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 2 p. 287 - 289
反应条件
trichlorophosphate 18 h; Heating / reflux;
参考文献
WO2005/49033 A1, ;
Page/Page column 110 ;
WO 2005/049033 A1
反应条件
phosphorus pentachloride; trichlorophosphate T=160°C; 2 h; Microwave irradiation;
参考文献
UNIVERSITE D'ORLEANS; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S); Routier, Sylvain; Guillaumet, Gérald; Tikad, Abdellatif; Dehbi, Oussama
Patent: US2013/109693 A1, 2013 ;
Location in patent: Paragraph 0252 - 0253 ;
反应条件
1: POCl3 2: NH3 3: ethanol 4: Raney nickel; aq. NaOH solution View Scheme
参考文献
Oakes et al.
Journal of the Chemical Society, 1956 , p. 1045,1053
反应条件
1: POCl3
2: NH3
3: water; H2S; NaHS
4: Raney nickel; aq.-ethanolic NH3
View Scheme
参考文献
Robins; Hitchings
Journal of the American Chemical Society, 1955 , vol. 77, p. 2256,2259
参考文献
McLean; Spring
Journal of the Chemical Society, 1949 , p. 2582,2584
反应条件
1: POCl3
2: H2O; NaHS
3: aqueous acetic acid; sodium acetate
View Scheme
参考文献
Robins; Hitchings
Journal of the American Chemical Society, 1955 , vol. 77, p. 2256,2259
反应条件
1: POCl3
2: NH3
3: ethanol
View Scheme
参考文献
Robins; Hitchings
Journal of the American Chemical Society, 1955 , vol. 77, p. 2256,2259