1: 2-butyl-1,3-diaza-spiro[4.4]non-1-en-4-one With sodium hydride in DMF (N,N-dimethyl-formamide) T=20°C; 0.5 h; 2: 4-bromomethyl-biphenyl-2-carbonitrile in DMF (N,N-dimethyl-formamide) T=20°C; 1 h;