pyridine; 1,8-diazabicyclo[5.4.0]undec-7-ene 15 h; Ambient temperature;

1: 2.5 g / pyridine / 15 h / Ambient temperature 2: 84 percent / dimethylformamide / 24 h / Ambient temperature 3: 73 percent / DBU, pyridine / 15 h / Ambient temperature View Scheme

1: 81 percent / pyridine / dimethylformamide / 4 h / 75 °C 2: 1.) PPh3, 2.) DEAD / 1.) dioxane, 80 deg C, 30 min, 2.) dioxane, 60 deg C, 2 h 3: NH3 / methanol / 15 h / Ambient temperature 4: HF, pyridine, t-BuONO / 2 h / -30 °C 5: 2.5 g / pyridine / 15 h / Ambient temperature 6: 84 percent / dimethylformamide / 24 h / Ambient temperature 7: 73 percent / DBU, pyridine / 15 h / Ambient temperature View Scheme

1: 2.5 g / pyridine / 15 h / Ambient temperature 2: 84 percent / dimethylformamide / 24 h / Ambient temperature 3: 73 percent / DBU, pyridine / 15 h / Ambient temperature View Scheme

1: HF, pyridine, t-BuONO / 2 h / -30 °C 2: 2.5 g / pyridine / 15 h / Ambient temperature 3: 84 percent / dimethylformamide / 24 h / Ambient temperature 4: 73 percent / DBU, pyridine / 15 h / Ambient temperature View Scheme

1: NH3 / methanol / 15 h / Ambient temperature 2: HF, pyridine, t-BuONO / 2 h / -30 °C 3: 2.5 g / pyridine / 15 h / Ambient temperature 4: 84 percent / dimethylformamide / 24 h / Ambient temperature 5: 73 percent / DBU, pyridine / 15 h / Ambient temperature View Scheme

1: 1.) PPh3, 2.) DEAD / 1.) dioxane, 80 deg C, 30 min, 2.) dioxane, 60 deg C, 2 h 2: NH3 / methanol / 15 h / Ambient temperature 3: HF, pyridine, t-BuONO / 2 h / -30 °C 4: 2.5 g / pyridine / 15 h / Ambient temperature 5: 84 percent / dimethylformamide / 24 h / Ambient temperature 6: 73 percent / DBU, pyridine / 15 h / Ambient temperature View Scheme

1: 84 percent / dimethylformamide / 24 h / Ambient temperature 2: 73 percent / DBU, pyridine / 15 h / Ambient temperature View Scheme