6-氯-α-(2,6-二氯苯基)-3-哒嗪甲腈合成路线 (共 2 条)
反应条件
1: 2,6-Dichlorophenylacetonitrile With potassium tert-butylate in tetrahydrofuran T=20°C; 2: 3,6-dichloro-pyridazine in tetrahydrofuran 2 h;
参考文献
Bagley, Mark C.; Davis, Terence; Dix, Matthew C.; Fusillo, Vincenzo; Pigeaux, Morgane; Rokicki, Michal J.; Kipling, David
Journal of Organic Chemistry, 2009 , vol. 74, # 21 p. 8336 - 8342
反应条件
trans-1,2-cyclohexanediol; potassium carbonate in isopropyl alcohol T=120°C; Ullmann type coupling; 3 h; Microwave irradiation;
参考文献
Bagley, Mark C.; Davis, Terence; Dix, Matthew C.; Fusillo, Vincenzo; Pigeaux, Morgane; Rokicki, Michal J.; Kipling, David
Journal of Organic Chemistry, 2009 , vol. 74, # 21 p. 8336 - 8342