3,4-双(溴代甲基)苯甲酸甲酯合成路线 （共 6 条）
反应条件
N-bromosuccinmide; dibenzoyl peroxide in dimethyl sulfoxide
参考文献
Hou, Duen-Ren; Wang, Ming-Shiang; Chung, Ming-Wen; Hsieh, Yih-Dar; Tsai, Hui-Hsu Gavin
Journal of Organic Chemistry, 2007 , vol. 72, # 24 p. 9231 - 9239
反应条件
N-bromosuccinmide; dibenzoyl peroxide
反应条件
hydrogen bromide in acetic acid; ethyl acetate
参考文献
Rational Drug Design Laboratories
Patent: US5698580 A1, 1997 ;
反应条件
1: Et3N / benzene / Heating 2: LiAlH4 / tetrahydrofuran / 25 °C 3: 86 percent / H2; aq. HCl / Pd/C / methanol / 25 °C / 3620.04 Torr 4: 94 percent / Et3N / CH2Cl2 / 25 °C View Scheme
参考文献
Le Bourdonnec, Bertrand; Ajello, Christopher W.; Seida, Pamela R.; Susnow, Roberta G.; Cassel, Joel A.; Belanger, Serge; Stabley, Gabriel J.; DeHaven, Robert N.; DeHaven-Hudkins, Diane L.; Dolle, Roland E.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2647 - 2652
反应条件
1: Et3N / benzene / Heating 2: LiAlH4 / tetrahydrofuran / 25 °C View Scheme
参考文献
Le Bourdonnec, Bertrand; Ajello, Christopher W.; Seida, Pamela R.; Susnow, Roberta G.; Cassel, Joel A.; Belanger, Serge; Stabley, Gabriel J.; DeHaven, Robert N.; DeHaven-Hudkins, Diane L.; Dolle, Roland E.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2647 - 2652
反应条件
1: Et3N / benzene / Heating 2: LiAlH4 / tetrahydrofuran / 25 °C 3: 86 percent / H2; aq. HCl / Pd/C / methanol / 25 °C / 3620.04 Torr View Scheme
参考文献
Le Bourdonnec, Bertrand; Ajello, Christopher W.; Seida, Pamela R.; Susnow, Roberta G.; Cassel, Joel A.; Belanger, Serge; Stabley, Gabriel J.; DeHaven, Robert N.; DeHaven-Hudkins, Diane L.; Dolle, Roland E.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2647 - 2652
