2-(哌啶-2-基)-1H-吲哚合成路线 （共 4 条）
反应条件
palladium 10 on activated carbon; hydrogen; acetic acid in methanol
T=50°C; P=60804.1 Torr; 24 h; Autoclave;
参考文献
MERCK PATENT GMBH; SCHIEMANN, Kai; STAEHLE, Wolfgang; BUSCH, Michael; WIENKE, Dirk; POESCHKE, Oliver; BURGER, Christa
Patent: WO2013/45028 A1, 2013 ;
Location in patent: Page/Page column 18; 19 ;
反应条件
1: ethanol
2: polyphosphoric acid / 130 °C
3: 82 percent / H2; acetic acid / PtO2 / 2585.74 Torr
View Scheme
参考文献
Jennings, Lee D.; Foreman, Ken W.; Rush III, Thomas S.; Tsao, Desiree H. H.; Mosyak, Lidia; Li, Yuanhong; Sukhdeo, Mohani N.; Ding, Weidong; Dushin, Elizabeth G.; Kenny, Cynthia Hess; Moghazeh, Soraya L.; Petersen, Peter J.; Ruzin, Alexey V.; Tuckman, Margareta; Sutherland, Alan G.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1427 - 1431
反应条件
1: polyphosphoric acid / 130 °C
2: 82 percent / H2; acetic acid / PtO2 / 2585.74 Torr
View Scheme
参考文献
Jennings, Lee D.; Foreman, Ken W.; Rush III, Thomas S.; Tsao, Desiree H. H.; Mosyak, Lidia; Li, Yuanhong; Sukhdeo, Mohani N.; Ding, Weidong; Dushin, Elizabeth G.; Kenny, Cynthia Hess; Moghazeh, Soraya L.; Petersen, Peter J.; Ruzin, Alexey V.; Tuckman, Margareta; Sutherland, Alan G.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1427 - 1431
反应条件
1: 100 percent / Na2CO3; n-Bu4NI
2: 79 percent / methanesulfonic acid / 55 °C
View Scheme
参考文献
Jennings, Lee D.; Foreman, Ken W.; Rush III, Thomas S.; Tsao, Desiree H. H.; Mosyak, Lidia; Li, Yuanhong; Sukhdeo, Mohani N.; Ding, Weidong; Dushin, Elizabeth G.; Kenny, Cynthia Hess; Moghazeh, Soraya L.; Petersen, Peter J.; Ruzin, Alexey V.; Tuckman, Margareta; Sutherland, Alan G.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1427 - 1431
