(2-甲氧基苯氧基)丙二酸二乙酯合成路线

参考文献

AUSPEX PHARMACEUTICALS, INC.
Patent: US2008/242687 A1, 2008 ;
Location in patent: Page/Page column 31-32; 33 ;
US 20080242687 A1

13052-77-2

20730-58-9(2-甲氧基苯氧基)丙二酸二乙酯

参考文献

Bischoff
Chemische Berichte, 1900 , vol. 33, p. 1395

20730-58-9(2-甲氧基苯氧基)丙二酸二乙酯

329923-15-14,6-二羟基-5-(2-甲氧基苯氧基)-2-(2-嘧啶基)嘧啶

参考文献

BIOCON LIMITED; VENKATA, Srinivas, Pullela; KOTHAKONDA, Kiran, Kumar; RAJMAHENDRA, Shanmughasamy; CHANDRASEKARAN, Indrajit; KALIAPPAN, Mariappan; MAILAR, Rekha, Shivappa
Patent: WO2013/57545 A1, 2013 ;
Location in patent: Paragraph 14 ;

312613-82-4+

20730-58-9(2-甲氧基苯氧基)丙二酸二乙酯

329923-15-14,6-二羟基-5-(2-甲氧基苯氧基)-2-(2-嘧啶基)嘧啶

参考文献

CADILA HEALTHCARE LIMITED; SATA, Kaushilk; PANDEY, Bipin
Patent: WO2010/32261 A1, 2010 ;
Location in patent: Page/Page column 6; 12-13; 24 ;

20730-58-9(2-甲氧基苯氧基)丙二酸二乙酯+

16879-48-42-嘧啶羧酰胺苯磺酸盐

329923-15-14,6-二羟基-5-(2-甲氧基苯氧基)-2-(2-嘧啶基)嘧啶

参考文献

Harada, Hironori; Kazami, Jun-ichi; Watanuki, Susumu; Tsuzuki, Ryuji; Sudoh, Katsumi; Fujimori, Akira; Sanagi, Masanao; Orita, Masaya; Nakahara, Hideaki; Shimaya, Jun; Tsukamoto, Shin-ichi; Tanaka, Akihiro; Yanagisawa, Isao
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 11 p. 2955 - 2968

20730-58-9(2-甲氧基苯氧基)丙二酸二乙酯

150727-72-3

参考文献

Bolli, Martin H.; Boss, Christoph; Clozel, Martine; Fischli, Walter; Hess, Patrick; Weller, Thomas
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 955 - 959

20730-58-9(2-甲氧基苯氧基)丙二酸二乙酯+

16879-48-42-嘧啶羧酰胺苯磺酸盐

150728-12-45-(2-甲氧基苯氧基)-[2,2'-二嘧啶]-4,6(1H,5H)-二酮

参考文献

AUSPEX PHARMACEUTICALS, INC.
Patent: US2008/242687 A1, 2008 ;
Location in patent: Page/Page column 32; 34 ;
US 20080242687 A1

20730-58-9(2-甲氧基苯氧基)丙二酸二乙酯

150728-13-5波生坦中间体(I)

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 5 p. 955 - 959

20730-58-9(2-甲氧基苯氧基)丙二酸二乙酯

150727-06-3波生坦中间体(II)

参考文献

BIOCON LIMITED; VENKATA, Srinivas, Pullela; KOTHAKONDA, Kiran, Kumar; RAJMAHENDRA, Shanmughasamy; CHANDRASEKARAN, Indrajit; KALIAPPAN, Mariappan; MAILAR, Rekha, Shivappa
Patent: WO2013/57545 A1, 2013 ;

20730-58-9(2-甲氧基苯氧基)丙二酸二乙酯

14007-09-12-(2-甲氧基苯氧基)-1,3-丙二醇

参考文献

Gierer,J.; Kunze,I.
Acta Chemica Scandinavica (1947-1973), 1961 , vol. 15, p. 803 - 807