1: Erwaermen des Reaktionsprodukts mit wss.Essigsaeure 2: palladium/BaSO4; aqueous ethanolic sodium acetate / Hydrogenation.behandlung mit methanol.NH3 View Scheme

trifluoroacetic acid Yield given;

1.1: 86 percent / imidazole; DMAP / dimethylformamide / 20 °C 2.1: N-bromosuccinimide; benzoyl peroxide / CCl4 / Heating 3.1: 491 mg / NaHCO3 / H2O; tetrahydrofuran / 20 °C 4.1: 24 percent / imidazole; DMAP / dimethylformamide / 20 °C 5.1: AcOH / H2O / Heating 6.1: NaOH / dimethylsulfoxide; H2O / 0.33 h / 20 °C 6.2: 41 percent / dimethylsulfoxide; H2O / 1.5 h 7.1: 77 percent / AIBN; Bu3SnH / toluene / 3 h / Heating 8.1: 100 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h View Scheme