5-氨基苯并噻吩-2-羧酸甲酯合成路线 （共 4 条）
反应条件
hydrogenchloride; tin(ll) chloride in water T=80°C; 1 h;
参考文献
S*BIO PTE LTD
Patent: WO2006/101454 A1, 2006 ;
Location in patent: Page/Page column 45 ;
WO 2006/101454 A1
反应条件
1.1: 66 percent / K2CO3 / dimethylformamide / 20 h / 25 °C 2.1: Fe / methanol / 12 h / Heating 2.2: 87 percent / aq. HCl / methanol / 2 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 122, # 27 p. 6382 - 6394
参考文献
Geron Corporation
Patent: US5863936 A1, 1999 ;
反应条件
1: 90 percent / tetrahydrofuran / 16 h / Heating 2: 89 percent / aq. NaOH / methanol / 4 h / 60 °C View Scheme
参考文献
Boger, Dale L.; Fink, Brian E.; Hedrick, Michael P.
Journal of the American Chemical Society, 2000 , vol. 122, # 27 p. 6382 - 6394
