4-(4-甲氧基苯基)丁酸甲酯合成路线 （共 18 条）
反应条件
sulfuric acid 3 h; Heating / reflux;
参考文献
LA JOLLA PHARMACEUTICAL COMPANY
Patent: WO2005/82343 A2, 2005 ;
Location in patent: Page/Page column 100 ;
反应条件
sulfuric acid in methanol
参考文献
Cano, Ivan Collado; Dominianni, Samuel James; Etgen, Garret Jay; Garcia-Paredes, Cristina; Johnston, Richard Duane; Letourneau, Michael Edward; Mantlo, Nathan Bryan; Martinelli, Michael John; Mayhugh, Daniel Ray; Saeed, Ashraf; Thompson, Richard Craig; Wang, Xiaodong; Coffey, David Scott; Schmid, Christopher Randall; Vicenzi, Jeffrey Thomas; Xu, Yanping
Patent: US2004/102500 A1, 2004 ;
反应条件
5-chloro-2-hydroxy-benzoic acid; boric acid; tris(4-methylphenyl)-phosphine; palladium diacetate P=20685.9 Torr; 18 h; Heating;
参考文献
Vieira, Tiago O.; Green, Mike J.; Alper, Howard
Organic Letters, 2006 , vol. 8, # 26 p. 6143 - 6145
反应条件
[Ir(dF(CF3)ppy)2(bpy)](PF6) in methanol; acetone T=20°C; Giese Free Radical Synthesis; 22 h; Inert atmosphereUV-irradiation;
参考文献
Yasu, Yusuke; Koike, Takashi; Akita, Munetaka
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 18 p. 3414 - 3420
参考文献
Jackman,L.M.; Haddon,V.R.
Journal of the American Chemical Society, 1974 , vol. 96, # 16 p. 5130 - 5138
反应条件
in acetone 10 h; Heating;
参考文献
Panda, Atulya Kumar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 2 p. 372 - 375
反应条件
1.1: hydrazine hydrate; potassium hydroxide / bis-(2-hydroxy-ethyl) ether / 1 h / Heating 1.2: 70 percent / bis-(2-hydroxy-ethyl) ether / 2 h / 180 °C 2.1: 65 percent / acetone / 10 h / Heating View Scheme
参考文献
Bachule, M. T.; Mane, R. B.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1998 , vol. 37, # 3 p. 281 - 284
反应条件
1.1: AlCl3 2.1: hydrazine hydrate; potassium hydroxide / bis-(2-hydroxy-ethyl) ether / 1 h / Heating 2.2: 70 percent / bis-(2-hydroxy-ethyl) ether / 2 h / 180 °C 3.1: 65 percent / acetone / 10 h / Heating View Scheme
参考文献
Bachule, M. T.; Mane, R. B.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1998 , vol. 37, # 3 p. 281 - 284
反应条件
potassium carbonate in acetone 10 h; Heating;
参考文献
Panda, Atulya Kumar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 2 p. 372 - 375
反应条件
copper(l) iodide; chloro-trimethyl-silane; N,N,N',N,-tetramethylethylenediamine; iodine; magnesium Yield given. Multistep reaction;
参考文献
Van Heerden, Pieter S.; Bezuidenhoudt, Barend C. B.; Ferreira, Daneel
Tetrahedron, 1996 , vol. 52, # 37 p. 12313 - 12322
