5-溴-1-甲基-1H-吲哚-2,3-二酮合成路线 （共 29 条）
反应条件
potassium carbonate in water Reflux;
参考文献
Sharma, Rashmi; Pandey, Anand Kumar; Shivahare, Rahul; Srivastava, Khushboo; Gupta, Suman; Chauhan, Prem M.S.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 298 - 301
反应条件
sodium hydride in N,N-dimethyl-formamide
T=20°C; 12 h;
参考文献
Beauchard, Anne; Ferandin, Yoan; Frere, Stephane; Lozach, Olivier; Blairvacq, Melina; Meijer, Laurent; Thiery, Valerie; Besson, Thierry
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 18 p. 6434 - 6443
反应条件
indium(III) chloride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in water; acetonitrile
T=80°C; 1.5 h;
参考文献
Yadav; Subba Reddy; Reddy, Ch. Suresh; Krishna
Synthesis, 2007 , # 5 p. 693 - 696
反应条件
copper(l) iodide; oxygen; 2,2,2-trimethylacetic acid in dimethyl sulfoxide
T=130°C; 23 h;
参考文献
Huang, Jinbo; Mao, Tingting; Zhu, Qiang
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2878 - 2882
反应条件
potassium carbonate in N,N-dimethyl-formamide
0.05 h; microwave irradiation;
参考文献
Azizian, Javad; Fallah-Bagher-Shaidaei, Hossain; Kefayati, Hassan
Synthetic Communications, 2003 , vol. 33, # 5 p. 789 - 793
反应条件
in 1,2-dichloro-benzene
T=160 - 165°C; 3 h;
参考文献
Majumdar, Krishna C.; Kundu, Anup K.; Chatterjee, Pranab
Journal of Chemical Research, Synopses, 1996 , # 10 p. 460 - 461
反应条件
1,4-diaza-bicyclo[2.2.2]octane in chloroform
Friedel-Crafts acylation; 22 h; Heating;
参考文献
Cheng, Ying; Ye, Hai-Ling; Zhan, Yu-Hua; Meth-Cohn, Otto
Synthesis, 2001 , # 6 p. 904 - 908
反应条件
air in chloroform
Cyclization; 18 h; Heating;
参考文献
Cheng, Ying; Liu, Qing-Xiang; Meth-Cohn, Otto
Tetrahedron Letters, 2000 , vol. 41, # 18 p. 3475 - 3478
参考文献
Kohn; Ostersetzer
Monatshefte fuer Chemie, 1913 , vol. 34, p. 783
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 20 °C / |Inert atmosphere
2: potassium carbonate / methanol / 2.5 h / 20 °C
3: hydrogenchloride; water / methanol / 12 h / 50 °C
4: copper(l) iodide; 2,2,2-trimethylacetic acid; oxygen / dimethyl sulfoxide / 23 h / 130 °C
View Scheme
参考文献
Huang, Jinbo; Mao, Tingting; Zhu, Qiang
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2878 - 2882
