3-(4-甲氧基苯基)-1-苯丙酮合成路线 （共 30 条）
反应条件
triethylamine in water
T=130°C; carbonylative Sonogashira coupling reaction; P=22502.3 Torr; 6 h; Autoclave;
参考文献
Wang, Yan; Liu, Jianhua; Xia, Chungu
Tetrahedron Letters, 2011 , vol. 52, # 14 p. 1587 - 1591
反应条件
copper(l) iodide; sodium lauryl sulfate; potassium carbonate; bis-triphenylphosphine-palladium(II) chloride in water
T=65°C; 4 h;
参考文献
Chen, Liang; Li, Chao-Jun
Organic Letters, 2004 , vol. 6, # 18 p. 3151 - 3153
反应条件
diethylamine; (Ph3P)2Pd2(Ph)2(μ-OH)2
T=90°C; P=11400 Torr; 2 h;
参考文献
Delaude; Masdeu; Alper
Synthesis, 1994 , # 11 p. 1149 - 1151
反应条件
copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride in acetonitrile
T=60°C; 8 h;
参考文献
Oh, Chang Ho; Reddy, V. Raghava
Tetrahedron Letters, 2004 , vol. 45, # 46 p. 8545 - 8548
反应条件
1: potassium trifluoro((4-methoxyphenyl)ethynyl)borate With boron trichloride in dichloromethane
T=20°C; 0.25 h; Inert atmosphereSonication;
2: benzoyl chloride in dichloromethane
T=20°C; Inert atmosphere;
参考文献
Taylor, Cassandra; Bolshan, Yuri
Organic Letters, 2014 , vol. 16, # 2 p. 488 - 491
反应条件
[Pd(η3-1-Ph-allyl)(μ-Cl)]2; potassium carbonate; di-(1-adamantyl)-n-butylphosphine in N,N-dimethyl-formamide
T=100°C; Carbonylative Sonogashira coupling; P=7500.75 Torr; 20 h; Inert atmosphere; chemoselective reaction;
参考文献
Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias
Chemistry - A European Journal, 2010 , vol. 16, # 40 p. 12104 - 12107
反应条件
[{Pd(cinnamyl)Cl}2]; triethylamine; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene
T=110°C; Sonogashira coupling; P=7500.75 Torr; 2 h; Inert atmosphereAutoclave;
参考文献
Wu, Xiao-Feng; Sundararaju, Basker; Neumann, Helfried; Dixneuf, Pierre H.; Beller, Matthias
Chemistry - A European Journal, 2011 , vol. 17, # 1 p. 106 - 110
反应条件
1: carbon monoxide; tri-phenyl-antimony With [bis(acetoxy)iodo]benzene in dichloromethane
T=20°C; 7 h;
2: 2-(4-methoxyphenyl)-1-trimethylsilyl-ethyne With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; copper(l) iodide in acetonitrile
T=50°C; 5 h; Further stages.;
参考文献
Kang, Suk-Ku; Ryu, Hyung-Chul; Hong, Young-Taek
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 7 p. 736 - 739
反应条件
bis-triphenylphosphine-palladium(II) chloride in 1,2-dichloro-ethane
T=80°C; Substitution;
参考文献
Kakusawa, Naoki; Yamaguchi, Kouichiro; Kurita, Jyoji; Tsuchiya, Takashi
Tetrahedron Letters, 2000 , vol. 41, # 21 p. 4143 - 4146
反应条件
copper(l) chloride in DMI
T=120°C; 0.5 h; Inert atmosphere;
参考文献
Nishihara, Yasushi; Saito, Daisuke; Inoue, Eiji; Okada, Yoshiaki; Miyazaki, Mikihiro; Inoue, Yoshiaki; Takagi, Kentaro
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 306 - 308
