1,2-二(苯基)丙-1-酮合成路线 （共 138 条）
反应条件
[Pd(η3-allyl)(Cl)((N,N′-bis-(2,6-diisopropylphenyl)imidazol-2-ylidene))]; potassium tert-butylate in toluene
T=80°C; 1.5 h; Inert atmosphere;
参考文献
Landers, Brant; Berini, Christophe; Wang, Chao; Navarro, Oscar
Journal of Organic Chemistry, 2011 , vol. 76, # 5 p. 1390 - 1397
反应条件
palladium diacetate in tetrahydrofuran
参考文献
Yale University
Patent: US6072073 A1, 2000 ;
反应条件
1: 3-phenyl-3-hydroxypropene With α-cyclohexylcyclohexanemethanamine in water
T=20°C; Heck reaction; 0.25 h;
2: iodobenzene With 4'-hydroxyacetophenone oxime palladacycle catalyst in water
T=120°C; Heck reaction; 10 h; Further stages.;
参考文献
Alacid, Emilio; Najera, Carmen
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2572 - 2584
反应条件
1: (2R*,3S*)-2-methyl-2,3-diphenyloxirane With sec.-butyllithium in tetrahydrofuran; hexane; cyclohexane
T=24°C; 0.0001 h;
2: methyl iodide in tetrahydrofuran; hexane; cyclohexane
T=24°C; 0.000555556 h; optical yield given as percent de;
参考文献
Nagaki, Aiichiro; Takizawa, Eiji; Yoshida, Jun-ichi
Journal of the American Chemical Society, 2009 , vol. 131, p. 1654 - 1655
反应条件
1: (2S*,3S*)-2-methyl-2,3-diphenyloxirane; sec.-butyllithium in tetrahydrofuran; hexane; cyclohexane
T=24°C; 0.0132222 h;
2: methyl iodide in tetrahydrofuran; hexane; cyclohexane
T=24°C; 0.000555556 h; optical yield given as percent de;
参考文献
Nagaki, Aiichiro; Takizawa, Eiji; Yoshida, Jun-ichi
Journal of the American Chemical Society, 2009 , vol. 131, p. 1654 - 1655
反应条件
1: (2S*,3S*)-2-methyl-2,3-diphenyloxirane; sec.-butyllithium in tetrahydrofuran; hexane; cyclohexane
T=24°C; 0.0264444 h;
2: methyl iodide in tetrahydrofuran; hexane; cyclohexane
T=24°C; 0.000555556 h;
参考文献
Nagaki, Aiichiro; Takizawa, Eiji; Yoshida, Jun-ichi
Journal of the American Chemical Society, 2009 , vol. 131, p. 1654 - 1655
反应条件
hydrogen; Co catalyst
参考文献
Takeuchi,S. et al.
Bulletin of the Chemical Society of Japan, 1974 , vol. 47, p. 463 - 466
反应条件
gallium(III) chloride; 2-methyl cyclohexane in 1,2-dichloro-ethane
T=80°C; 1 h;
参考文献
Oshita, Masayuki; Okazaki, Takao; Ohe, Kouichi; Chatani, Naoto
Organic Letters, 2005 , vol. 7, # 2 p. 331 - 334
反应条件
1: 3-phenyl-3-hydroxypropene With α-cyclohexylcyclohexanemethanamine in water
T=20°C; Heck reaction; 0.25 h;
2: iodobenzene With Kaiser oxime-derived complex on resin base in water
T=120°C; Heck reaction; 16 h; Further stages. Title compound not separated from byproducts.;
参考文献
Alacid, Emilio; Najera, Carmen
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2572 - 2584
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
T=20°C; 1.5 h;
参考文献
Ooi; Ooi, Takashi; Sugimoto; Sugimoto, Hayato; Maruoka; Maruoka, Keiji
Heterocycles, 2001 , vol. 54, # 2 p. 593 - 596
