3-(4-甲氧基苯基)丙醛合成路线 （共 75 条）
反应条件
1: sodium hydride / tetrahydrofuran
2: hydrogen; palladium on activated charcoal / ethyl acetate
3: sodium hydroxide / ethanol
View Scheme
参考文献
Mimori, Seisuke; Okuma, Yasunobu; Kaneko, Masayuki; Kawada, Koichi; Nomura, Yasuyuki; Murakami, Yasuoki; Hamana, Hiroshi
Chemistry Letters, 2013 , vol. 42, # 9 p. 1051 - 1052
反应条件
ammonium hydroxide; hydrogen cyanide
Erhitzen des Reaktionsgemisches mit wss. Schwefelsaeure auf 125grad und anschliessend mit Bariumcarbonat;
参考文献
Evans; Walker
Journal of the Chemical Society, 1947 , p. 1571
反应条件
1: toluene / 0.33 h / |Inert atmosphere; |Reflux
2: hydrogen; palladium on activated charcoal / ethanol / 10 h / 20 °C / |Inert atmosphere
3: hydrogen bromide / acetic acid / 3 h / |Inert atmosphere; |Reflux
View Scheme
参考文献
Thuaud, Frederic; Kojima, Shuntaro; Hirai, Go; Oonuma, Kana; Tsuchiya, Ayako; Uchida, Takako; Tsuchimoto, Teruhisa; Sodeoka, Mikiko
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 9 p. 2771 - 2782
反应条件
sodium hydride; dimethyl sulfoxide
1.) 65 deg C, 1.5 h, 2.) THF, 0 deg C, 0.5 h; 25 deg C, 2 h;
参考文献
Semmelhack, M.F.; Helquist, Paul; Jones, L.D.; Keller, Leonard; Mendelson L.; et al.
Journal of the American Chemical Society, 1981 , vol. 103, # 21 p. 6460 - 6471
反应条件
boron trifluoride diethyl etherate in dichloromethane
1.) 0 deg C, 0.5 h, 2.) 25 deg C, 1.5 h;
参考文献
Semmelhack, M.F.; Helquist, Paul; Jones, L.D.; Keller, Leonard; Mendelson L.; et al.
Journal of the American Chemical Society, 1981 , vol. 103, # 21 p. 6460 - 6471
