3-(4-甲氧基苯基)丙醛合成路线 （共 75 条）
反应条件
oxalyl dichloride; triethylamine in dichloromethane; dimethyl sulfoxide T=-78°C; Swern oxidation; 0.5 h; Inert atmosphere;
参考文献
Bercovici, Daniel A.; Brewer, Matthias
Journal of the American Chemical Society, 2012 , vol. 134, # 24 p. 9890 - 9893
反应条件
methylphenylsilane; trimethylacetic anhydride; tris(4-methylphenyl)-phosphine; bis(dibenzylideneacetone)-palladium(0) in toluene T=60°C; 20 h; Schlenk techniqueInert atmosphere;
参考文献
Fujihara, Tetsuaki; Cong, Cong; Terao, Jun; Tsuji, Yasushi
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 17 p. 3420 - 3424
反应条件
triethylsilane; trimesitylphosphane; bis(dibenzylideneacetone)-palladium(0) in toluene T=40°C; 1.5 h; Schlenk techniqueInert atmosphere;
参考文献
Fujihara, Tetsuaki; Cong, Cong; Iwai, Tomohiro; Terao, Jun; Tsuji, Yasushi
Synlett, 2012 , vol. 23, # 16 art. no. ST-2012-U0571-L, p. 2389 - 2392
反应条件
1: With diisobutylaluminium hydride in toluene T=-78°C; 1 h; 2: With ammonium chloride in water
参考文献
Takeda Pharmaceutical Company Limited
Patent: US2011/39893 A1, 2011 ;
Location in patent: Page/Page column 29 ;
反应条件
1: With phenyl silane; 4-methylmorpholine N-oxide; hexacarbonyl molybdenum in tetrahydrofuran T=80°C; 16 h; 2: With water in tetrahydrofuran T=20°C; 0.25 h; Further stages.;
参考文献
Frost, Christopher G.; Hartley, Benjamin C.
Organic Letters, 2007 , vol. 9, # 21 p. 4259 - 4261
反应条件
1: With methyl-diethoxy-silane; Rh(t-Bu-Phebox)(OAc)2(aq) in toluene T=60°C; 2: With potassium fluoride; tetrabutyl ammonium fluoride in tetrahydrofuran; methanol; toluene Further stages.;
参考文献
Kanazawa, Yoshinori; Nishiyama, Hisao
Synlett, 2006 , # 19 p. 3343 - 3345
反应条件
ammonium formate; PdMCM-41 in methanol T=69.84°C; 3 h;
参考文献
He, Rongjun; Toy, Patrick H.; Lam, Yulin
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 1 p. 54 - 60
反应条件
hydrogen; [rhodium(I)(carbonyl)2(acetylacetonate)]; (R,S)-Ph2P-binaphthyl-cyclic binaphthylphosphoramidite in benzene T=60°C; P=15200 Torr; 24 h;
参考文献
Journal of the American Chemical Society, , vol. 128, # 22 p. 7198 - 7202
反应条件
hydrogen; tin(ll) chloride; ((2S,4S)-N-(tert-butoxycarbonyl)-4-(diphenylphosphino)-2-{(diphenylphosphino)methyl}pyrrolidine)PtCl2 in benzene T=60°C; P=137044 Torr; 8 h; Yield given. Yields of byproduct given;
参考文献
Journal of the American Chemical Society, , vol. 109, # 23 p. 7122 - 7127
反应条件
diisobutylaluminium hydride in dichloromethane T=-80°C;
参考文献
Rogano, Frank; Froidevaux, Georges; Rueedi, Peter
Helvetica Chimica Acta, 2010 , vol. 93, # 7 p. 1299 - 1312
