2-氨基-5-氯苯并噻唑合成路线 （共 17 条）
反应条件
benzyltrimethylammonium bromide dibromide in acetic acid T=20°C; 14 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 14 p. 4839 - 4843
反应条件
bromine; acetic acid T=0 - 20°C; 13.75 h;
参考文献
Asian Journal of Chemistry, , vol. 23, # 9 p. 3969 - 3974
反应条件
1: With bromine in chloroform T=0 - 5°C; Reflux; 2: With ammonia in water
参考文献
Medicinal Chemistry Research, , vol. 21, # 7 p. 1136 - 1148
反应条件
bromine; acetic acid T=0 - 20°C;
参考文献
Medicinal Chemistry Research, , vol. 20, # 7 p. 1033 - 1041
反应条件
Ni(PEt3)2Cl2; sodium cyanoborohydride in N,N-dimethyl-formamide T=60°C; 20 h;
参考文献
Chemistry Letters, , p. 265 - 266
反应条件
hydrogenchloride; tin in water T=20 - 100°C;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 17, # 24 p. 8206 - 8220
反应条件
1: hydrogenchloride / water / Heating 2: bromine / tetrachloromethane View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 48, # 6 p. 1351 - 1355
反应条件
1: morpholine / dichloromethane / 4 h / 20 °C 2: benzyltrimethylammonium bromide dibromide / acetic acid / 14 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 14 p. 4839 - 4843
反应条件
1.1: hydrogenchloride / water / 0.5 h / Reflux 1.2: 4 h / 20 °C / Reflux 2.1: bromine / chloroform / 0 - 5 °C / Reflux View Scheme
参考文献
Medicinal Chemistry Research, , vol. 21, # 7 p. 1136 - 1148
反应条件
bromine; acetic acid T=0 - 20°C;
参考文献
Chemistry of Heterocyclic Compounds, , vol. 45, # 11 p. 1343 - 1353
