5,6-二氯-1H-苯并[d]咪唑-2(3H)-酮合成路线 （共 5 条）
反应条件
in tetrahydrofuran T=20°C;
参考文献
ABBOTT GMBH and CO. KG
Patent: WO2008/25736 A1, 2008 ;
Location in patent: Page/Page column 61-62 ;
WO 2008/025736 A1
反应条件
sulfuryl dichloride in acetic acid Ambient temperature;
参考文献
Meanwell; Sit; Gao; Wong; St. Laurent; Balasubramanian
Journal of Organic Chemistry, 1995 , vol. 60, # 6 p. 1565 - 1582
反应条件
in pentan-1-ol 9 h; Heating;
参考文献
Townsend, Leroy B.; Devivar, Rodrigo V.; Turk, Steven R.; Nassiri, M. Reza; Drach, John C.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 20 p. 4098 - 4105
参考文献
Freeman, Stephen
Patent: US2003/191127 A1, 2003 ;
反应条件
1: With trichlorophosphate 3 h; Reflux; 2: With sodium hydroxide in water T=20°C; pH=7.0;
参考文献
JANSSEN PHARMACEUTICA NV
Patent: WO2009/134750 A1, 2009 ;
Location in patent: Page/Page column 60 ;
