5-(3-氟苯基)-1,3,4-噁二唑-2-硫醇合成路线 （共 6 条）
反应条件
hydrogenchloride in water T=0 - 5°C;
参考文献
Li, Liangjing; Ding, Hao; Wang, Baogang; Yu, Shichong; Zou, Yan; Chai, Xiaoyun; Wu, Qiuye
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 192 - 194
反应条件
potassium hydroxide in ethanol Heating;
参考文献
Xu, Wei-Ming; Han, Fei-Fei; He, Ming; Hu, De-Yu; He, Jiang; Yang, Song; Song, Bao-An
Journal of Agricultural and Food Chemistry, 2012 , vol. 60, # 4 p. 1036 - 1041
反应条件
1: hydrazine hydrate / methanol 2: potassium hydroxide / ethanol View Scheme
参考文献
Li, Liangjing; Ding, Hao; Wang, Baogang; Yu, Shichong; Zou, Yan; Chai, Xiaoyun; Wu, Qiuye
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 192 - 194
反应条件
1: sulfuric acid 2: hydrazine hydrate / methanol 3: potassium hydroxide / ethanol View Scheme
参考文献
Li, Pei; Yin, Juan; Xu, Weiming; Wu, Jian; He, Ming; Hu, Deyu; Yang, Song; Song, Baoan
Chemical Biology and Drug Design, 2013 , vol. 82, # 5 p. 546 - 556
反应条件
1: triethylamine / dichloromethane / 0 °C 2: hydrazine hydrate / methanol / 5 h / |Reflux 3: potassium hydroxide / methanol / 20 °C / |Reflux 4: hydrogenchloride / water / 0 - 5 °C View Scheme
参考文献
Li, Liangjing; Ding, Hao; Wang, Baogang; Yu, Shichong; Zou, Yan; Chai, Xiaoyun; Wu, Qiuye
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 192 - 194
反应条件
1: potassium hydroxide / methanol / 20 °C / |Reflux 2: hydrogenchloride / water / 0 - 5 °C View Scheme
参考文献
Li, Liangjing; Ding, Hao; Wang, Baogang; Yu, Shichong; Zou, Yan; Chai, Xiaoyun; Wu, Qiuye
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 192 - 194
