7-甲氧基-2,2-二甲基苯并二氢吡喃-4-酮合成路线 （共 31 条）
反应条件
1: 80 percent / POCl3, ZnCl2 / 2 h / 50 °C 2: 94 percent / K2CO3, KI / dimethylformamide / 3 h / 80 °C View Scheme
参考文献
Bridge et al.
Journal of the Chemical Society, 1937 , p. 1530,1534
反应条件
pyrrolidine in toluene 1) 24 h, 2) heating;
参考文献
Kabbe, Hans-Joachim; Widdig, Arno
Angewandte Chemie, 1982 , vol. 94, # 4 p. 254 - 262
反应条件
1: 3-methyl-2-butenoic acid With boron trifluoride diethyl etherate; trichlorophosphate T=0°C; Substitution; 0.25 h; 2: 1,3-dimethoxy benzene T=25°C; Acylation; Friedel-Crafts reaction; 24 h;
参考文献
Jain, Niveta; Krishnamurty
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 11 p. 1237 - 1241
反应条件
1: 85 percent / magnesium / benzene / 11 h / Heating 2: 28 percent / potassium carbonate / hexane / 20 h / Irradiation 3: 98 percent / 10percent aq. sodium hydroxide / hexane / 4 h / Ambient temperature View Scheme
参考文献
Bridge et al.
Journal of the Chemical Society, 1937 , p. 1530,1534
反应条件
methanesulfonic acid; phosphorus pentoxide T=70°C; 1 h;
参考文献
Camps, F.; Coll, J.; Messeguer, A.; Pericas, M. A.; Ricart, S.; et al.
Synthesis, 1980 , # 9 p. 725 - 727
反应条件
1: 92 percent / N,N-dicyclohexylcarbodiimide, 4-dimethylaminopyridine / CH2Cl2 / 6 h / Ambient temperature 2: 37 percent / AlCl3 / nitromethane / 3 h / 70 °C View Scheme
参考文献
Miranda, Miguel A.; Primo, Jaime; Tormos, Rosa
Heterocycles, 1988 , vol. 27, # 3 p. 673 - 682
反应条件
potassium carbonate; acetone
参考文献
Janeczko, Tomasz; Dmochowska-Gladysz, Jadwiga; Szumny, Antoni; Kostrzewa-Suslow, Edyta
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 97, p. 278 - 282
反应条件
aluminium trichloride in nitromethane T=70°C; 3 h;
参考文献
Camps; Coll; Colomina; Messeguer
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 2 p. 363 - 368
反应条件
methanesulfonic acid T=70°C; 1.5 h;
参考文献
Camps; Coll; Colomina; Messeguer
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 2 p. 363 - 368
反应条件
1: 28 percent / potassium carbonate / hexane / 20 h / Irradiation 2: 98 percent / 10percent aq. sodium hydroxide / hexane / 4 h / Ambient temperature View Scheme
参考文献
Miranda, Miguel A.; Primo, Jaime; Tormos, Rosa
Heterocycles, 1988 , vol. 27, # 3 p. 673 - 682
