5-甲氧基-异邻苯二甲酸二甲酯合成路线 （共 24 条）
反应条件
1.1: potassium hydroxide; hydrogenchloride / water / 24 h / |Inert atmosphere 1.2: 0.67 h / |Inert atmosphere; |Cooling with ice 2.1: 1H-imidazole / dichloromethane / 1.5 h / |Inert atmosphere; |Cooling with ice View Scheme
参考文献
Fretz, Samuel J.; Hadad, Christopher M.; Hart, David J.; Vyas, Shubham; Yang, Dexi
Journal of Organic Chemistry, 2013 , vol. 78, # 1 p. 83 - 92
反应条件
diisobutylaluminium hydride in tetrahydrofuran
T=20°C;
参考文献
Genetech, Inc.; Curis, Inc.; Cai, Xiong; Qian, Changgeng; Zhai, Haixiao
Patent: US2014/18368 A1, 2014 ;
Location in patent: Paragraph 0162; 0248; 0249 ;
反应条件
1: 83 percent / 85 percent KOH / methanol; tetrahydrofuran / 6 h / Heating
2: 90 percent / BH3*(CH3)2S / tetrahydrofuran / 0 - 60 °C
3: 91 percent / MnO2 / ethyl acetate / 5 h / Heating
View Scheme
参考文献
Zhao; Thurkauf
Synthetic Communications, 2001 , vol. 31, # 12 p. 1921 - 1926
反应条件
1: 81 percent / 85 percent KOH / tetrahydrofuran / Heating
2: 90 percent / BH3*(CH3)2S / tetrahydrofuran / 0 - 60 °C
View Scheme
参考文献
Zhao; Thurkauf
Synthetic Communications, 2001 , vol. 31, # 12 p. 1921 - 1926
