(R)-2-羟基-4-甲基戊酸合成路线 （共 19 条）
反应条件
sulfuric acid; sodium nitrite in water T=5 - 20°C;
参考文献
Pettit, George R.; Hu, Shougang; Knight, John C.; Chapuis, Jean-Charles
Journal of Natural Products, 2009 , vol. 72, # 3 p. 372 - 379
反应条件
lithium hydroxide in tetrahydrofuran 3 h; Ambient temperature;
参考文献
Mikami, Koichi; Terada, Masahiro; Nakai, Takeshi
Journal of the American Chemical Society, 1990 , vol. 112, # 10 p. 3949 - 3954
反应条件
phosphate buffer; D-glucose; 2-hydroxyethanethiol; sodium chloride; formate dehydrogenase; NADH-H+; benzoylformate reductase; bovine serum albumin; yeast alcohol dehydrogenase in ethanol; water; toluene T=30°C; 24 h;
参考文献
Yamazaki, Yoshimitsu; Maeda, Hidekatsu
Agricultural and Biological Chemistry, 1986 , vol. 50, # 10 p. 2621 - 2632
反应条件
hydrogenchloride in dichloromethane
参考文献
Kunz, Horst; Lerchen, Hans-Georg
Tetrahedron Letters, 1987 , vol. 28, # 17 p. 1873 - 1876
反应条件
BIS-TRIS buffer; Lactobacillus paracasei DSM 20207 in water T=42°C; pH=6; 24 h;
参考文献
Journal of Organic Chemistry, , vol. 70, # 10 p. 4028 - 4032
反应条件
in water T=24.84°C; pH=7; Neutral conditionsPhotolysisInert atmosphere;
参考文献
Nishino, Hideo; Hosaka, Masahito; Katoh, Masahiro; Inoue, Yoshihisa
Chemistry - A European Journal, 2013 , vol. 19, # 41 p. 13929 - 13936
反应条件
ozone in ethyl acetate
参考文献
Journal of Organic Chemistry, , vol. 41, # 22 p. 3497 - 3505
反应条件
triethylamine; bis[(1S,2R,3S,5S)-pinan-3-yl]chloroborane in tetrahydrofuran 1.) -20 deg C, 5 min; 2.) -20 deg C, then 0 deg C, 3 h; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 39, # 31 p. 5501 - 5504
反应条件
1: diluted sulfuric acid 2: dog's liver; ammonium carbonate View Scheme
参考文献
Journal of Biological Chemistry, , vol. 18, p. 38
Journal of the Chemical Society, , vol. 105, p. 2461
参考文献
Journal of Biological Chemistry, , vol. 18, p. 38
Journal of the Chemical Society, , vol. 105, p. 2461
