5-硝基-1H-咪唑-4-羧酸甲酯合成路线 （共 6 条）
反应条件
1: 1H-imidazole-4-carboxylic acid With ammonium nitrate; sulfuric acid T=100°C; 48 h; 2: methanol T=60°C; 24 h; 3: With ammonia in water
参考文献
MERCK SHARP and DOHME LIMITED; HOLLINGWORTH, Gregory, John; JONES, A., Brian; SPAREY, Timothy, Jason
Patent: WO2005/49613 A1, 2005 ;
Location in patent: Page/Page column 44 ;
WO 2005/049613 A1
参考文献
Windaus; Langenbeck
Chemische Berichte, 1923 , vol. 56, p. 684
参考文献
Kulew; Roshkow
Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 1389;engl.Ausg.S.1470
反应条件
hydrogen; palladium 10 on activated carbon in methanol; ethanol 4 h;
参考文献
MERCK SHARP and DOHME LIMITED; HOLLINGWORTH, Gregory, John; JONES, A., Brian; SPAREY, Timothy, Jason
Patent: WO2005/49613 A1, 2005 ;
Location in patent: Page/Page column 44 ;
WO 2005/049613 A1
反应条件
ethanol; silver nitrate Erhitzen des Reaktionsprodukts mit Tri-O-benzoyl-ξ-D-ribofuranosylchlorid in Xilol und Behandeln des Reaktionsprodukts mit methanol.NH3;
参考文献
Baddiley et al.
Journal of the Chemical Society, 1959 , p. 2893,2897,2900
反应条件
sodium hydroxide; hydroxylamine
参考文献
Taylor et al.
Journal of Organic Chemistry, 1959 , vol. 24, p. 2019
