1: para-chloroacetophenone With 2,6-diisopropoxyphenyl(dicyclohexyl)phosphonium tetrafluoroborate; palladium diacetate; potassium hydroxide in toluene T=20°C; 0.0666667 h; Inert atmosphere; 2: 4-aminoacetophenone in toluene T=110°C; 2 h; Inert atmosphere;

palladium 10 on activated carbon; sodium t-butanolate; 2-dicyclohexylphosphino-1,1'-biphenyl in tert-butyl alcohol T=80°C; Buchwald-Hartwig amination; Inert atmosphere;

lithium perchlorate; potassium carbonate; platinum; mercury in acetonitrile T=0°C; 3 h; Electrochemical reaction;