1: With n-butyllithium; 4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran
T=-78°C; Metallation; addition;
2: With water in tetrahydrofuran
T=-78 - 20°C; Hydrolysis;
3: With toluene-4-sulfonic acid in benzene
Cyclization; Heating;
参考文献
Pastor, Isidro M.; Yus, Miguel
Tetrahedron Letters, 2000 , vol. 41, # 28 p. 5335 - 5339
sodium ethanolate in diethyl ether
20 h; Ambient temperature;
参考文献
Sakai, Takashi; Yamawaki, Akitoshi; Katayama, Tsuyoshi; Okada, Hiroshi; Utaka, Masanori; Takeda, Akira
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 3 p. 1067 - 1070
potassium hydroxide in ethanol
3 h; Ambient temperature;
参考文献
Sakai, Takashi; Yamawaki, Akitoshi; Katayama, Tsuyoshi; Okada, Hiroshi; Utaka, Masanori; Takeda, Akira
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 3 p. 1067 - 1070
