1,3,3-三甲基-2,3-二氢-1H-吲哚-2-酮合成路线 （共 67 条）
反应条件
methylmagnesium bromide in tetrahydrofuran
4 h; Heating;
参考文献
Clark, Andrew J.; Davies, David I.; Jones, Keith; Millbanks, Christopher
Journal of the Chemical Society, Chemical Communications, 1994 , # 1 p. 41 - 42
反应条件
1: 53 percent / pyridine / diethyl ether / 4 h
2: 55 percent / CuBr; N,N,N',N',N''-pentamethyldiethylenetriamine; Cu / benzene / 1 h
3: 63 percent / 2-methyl-propan-2-ol / 2 h / 80 °C
View Scheme
参考文献
Leroi, Corinne; Bertin, Denis; Dufils, Pierre-Emmanuel; Gigmes, Didier; Marque, Sylvain; Tordo, Paul; Couturier, Jean-Luc; Guerret, Olivier; Ciufolini, Marco A.
Organic Letters, 2003 , vol. 5, # 26 p. 4943 - 4945
反应条件
sodium hydride; benzene
anschliessend mit Methyljodid;
参考文献
Wenkert et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 797,798
反应条件
ethanol; sodium ethanolate
参考文献
Julian et al.
Journal of the American Chemical Society, 1934 , vol. 56, p. 1797,1800
反应条件
1: 96 percent / Et3N / CH2Cl2 / 6 h / 20 °C
2: 89 percent / PCy3; Pd(OAc)2; NaO-t-Bu / dioxane / 3 h / 70 °C
View Scheme
参考文献
Lee; Hartwig
Journal of Organic Chemistry, 2001 , vol. 66, # 10 p. 3402 - 3415
反应条件
pyridine
T=23°C; 16 h;
参考文献
Mekhael, Maged K. G.; Smith, Richard J.; Bienz, Stefan; Linden, Anthony; Heimgartner, Heinz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2002 , vol. 57, # 4 p. 444 - 452
反应条件
in 1,4-dioxane
Heating;
参考文献
Prizhiyalgovskaya, N. M.; Kon'kov, L. I.; Tarshits, D. L.; Salmina, S. V.; Segizova, N. T.; Suvorov, N. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 7 p. 751 - 754
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , # 7 p. 915 - 918
反应条件
methyllithium; calcium carbonate
T=230 - 260°C;
参考文献
Brunner
Monatshefte fuer Chemie, 1896 , vol. 17, p. 484
参考文献
Brunner
Monatshefte fuer Chemie, 1897 , vol. 18, p. 533
反应条件
1: 81.5 percent / BF3*OEt2 / diethyl ether / 12 h / 23 °C
2: 20 percent / pyridine / 16 h / 23 °C
View Scheme
参考文献
Mekhael, Maged K. G.; Smith, Richard J.; Bienz, Stefan; Linden, Anthony; Heimgartner, Heinz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2002 , vol. 57, # 4 p. 444 - 452
