1,3,3-三甲基-2,3-二氢-1H-吲哚-2-酮合成路线 （共 67 条）
反应条件
in tetrahydrofuran
1 h;
参考文献
Goehring, R. Richard; Sachdeva, Yesh P.; Pisipati, Jyothi S.; Sleevi, Mark C.; Wolfe, James F.
Journal of the American Chemical Society, 1985 , vol. 107, # 2 p. 435 - 443
反应条件
NaY zeolite in dichloromethane
4 h; Heating;
参考文献
Casades; Alvaro; Garcia; Espla
Chemical Communications, 2001 , # 11 p. 982 - 983
反应条件
trichlorophosphate in 1,4-dioxane
T=80°C; 4 h; Yields of byproduct given;
参考文献
Prizhiyalgovskaya, N. M.; Kon'kov, L. I.; Tarshits, D. L.; Salmina, S. V.; Segizova, N. T.; Suvorov, N. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 7 p. 751 - 754
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , # 7 p. 915 - 918
反应条件
water in tetrahydrofuran
72 h; Heating;
参考文献
Mekhael, Maged K. G.; Smith, Richard J.; Bienz, Stefan; Linden, Anthony; Heimgartner, Heinz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2002 , vol. 57, # 4 p. 444 - 452
反应条件
1.1: 85 percent / 80
2.1: t-BuLi
2.2: BEt3
2.3: 30 percent / Pd(OAc)2 / tetrahydrofuran / 6 h / Heating
View Scheme
参考文献
Ishikura, Minoru; Takahashi, Norinobu; Yamada, Koji; Yanada, Reiko
Tetrahedron, 2006 , vol. 62, # 50 p. 11580 - 11591
反应条件
1.1: t-BuLi
1.2: BEt3
1.3: 30 percent / Pd(OAc)2 / tetrahydrofuran / 6 h / Heating
View Scheme
参考文献
Ishikura, Minoru; Takahashi, Norinobu; Yamada, Koji; Yanada, Reiko
Tetrahedron, 2006 , vol. 62, # 50 p. 11580 - 11591
反应条件
10 Au/Co3O4; hydrogen in n-heptane
T=90°C; P=45004.5 Torr; 24 h; Autoclave;
参考文献
Liu, Xiaohao; Hamasaki, Akiyuki; Yamane, Yoshihiro; Aikawa, Shohei; Ishida, Tamao; Haruta, Masatake; Tokunaga, Makoto
Catalysis Science and Technology, 2013 , vol. 3, # 11 p. 3000 - 3006
反应条件
Catalyst M-Chromium oxide; sulfuric acid
参考文献
Ciamician; Piccinini
Chemische Berichte, 1896 , vol. 29, p. 2469
Gazzetta Chimica Italiana, 1897 , vol. 27 I, p. 341
反应条件
1: tert-butyl N-indolecarboxylate With tert.-butyl lithium
2: With triethyl borane
3: N,2-dimethyl-N-(2-iodophenyl)acrylamide With palladium diacetate in tetrahydrofuran
6 h; Heating;
参考文献
Ishikura, Minoru; Takahashi, Norinobu; Yamada, Koji; Yanada, Reiko
Tetrahedron, 2006 , vol. 62, # 50 p. 11580 - 11591
反应条件
1: 97 percent / Et3N / tetrahydrofuran / 20 °C
2: 87 percent / diethyl phosphine oxide; 4-(3-CO2H-1-CN-1-Me-propylazo)-4-CN-4-Me-butyric acid / H2O / 168 h / 80 °C
View Scheme
参考文献
Khan, Tanweer A.; Tripoli, Regis; Crawford, James J.; Martin, Concepcion G.; Murphy, John A.
Organic Letters, 2003 , vol. 5, # 16 p. 2971 - 2974
