3-(3,5-二叔丁基-4-羟基苯基)丙酸合成路线 （共 16 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; Catalytic hydrogenation; P=2585.81 Torr; 3 h;
参考文献
Bebbington, David; Monck, Nathaniel J. T.; Gaur, Suneel; Palmer, Alan M.; Benwell, Karen; Harvey, Victoria; Malcolm, Craig S.; Porter, Richard H. P.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 15 p. 2779 - 2782
参考文献
Ciba-Geigy Corporation
Patent: US4713475 A1, 1987 ;
反应条件
in N,N-dimethyl-formamide T=20°C; electrolysis, in 0.1M tetraethylammonium perchlorate, E=-1.95 V(rel.s.c.e.);
参考文献
Volod'kin, A. A.; Malysheva, R. D.; Ershov, V. V.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1982 , vol. 31, # 7 p. 1417 - 1420
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1982 , # 7 p. 1594 - 1597
参考文献
Journal of the American Chemical Society, , vol. 79, p. 5019,5021
反应条件
sodium hydroxide; nickel monoaluminide
参考文献
Journal of the American Chemical Society, , vol. 79, p. 5019,5021
反应条件
1: acrylonitrile 2: aq.-ethanolic NaOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 79, p. 5019,5021
反应条件
1: 58 percent / aq. KOH, O2 / ethanol / 8 h / 40 - 45 °C 2: 100 percent / dimethylformamide / 20 °C / electrolysis, in 0.1M tetraethylammonium perchlorate, E=-1.95 V(rel.s.c.e.) View Scheme
参考文献
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 31, # 7 p. 1417 - 1420
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 7 p. 1594 - 1597
反应条件
in chloroform T=20°C; Kinetics; Further Variations:Solvents;
参考文献
Aref'ev; Belostotskaya; Vol'Eva; Domnina; Komissarova; Sergeeva; Khrustaleva
Russian Chemical Bulletin, 2007 , vol. 56, # 4 p. 781 - 790
反应条件
hydrogen bromide 2 h; Heating;
参考文献
Prosenko; Skorobogatov; Dyubchenko; Pinko; Kandalintseva; Shakirov; Pokrovsky
Russian Chemical Bulletin, 2007 , vol. 56, # 6 p. 1119 - 1124
反应条件
1: thionyl chloride; DMF / toluene; CH2Cl2 / 2 h / 20 °C 2: 28.6 g / NH4OH / tetrahydrofuran / 0.25 h / 0 °C 3: 45 percent / LiAlH4 / diethyl ether / 5.5 h / Heating View Scheme
参考文献
Bebbington, David; Monck, Nathaniel J. T.; Gaur, Suneel; Palmer, Alan M.; Benwell, Karen; Harvey, Victoria; Malcolm, Craig S.; Porter, Richard H. P.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 15 p. 2779 - 2782
