乙基(2E)-2-氰基-3-(4-甲基苯基)丙烯酸酯合成路线 （共 9 条）
反应条件
L-proline Knoevenagel condensation; 0.0833333 h; microwave irradiation;
参考文献
Oskooie, Hossein A.; Roomizadeh, Elham; Heravi, Majid M.
Journal of Chemical Research, 2006 , # 4 p. 246 - 247
反应条件
ammonium acetate in methanol T=20°C; Knoevenagel condensation; 0.0833333 h;
参考文献
Heterocycles, , vol. 73, # C p. 795 - 804
反应条件
Na8H[PW9O34]*7H2O in methanol T=25°C; Knoevenagel Condensation; 6 h; Overall yield = 85 percent; Overall yield = 89 percentChromat.;
参考文献
Applied Catalysis A: General, , vol. 475, p. 140 - 146
反应条件
1: aq. HCl; acetone / 0.5 h / 20 °C 2: acetic acid; pyrrolidine / benzene / 2 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 8 p. 2620 - 2626
反应条件
1.1: Mg / tetrahydrofuran / 1 h / Heating 1.2: tetrahydrofuran / 2 h / Heating 2.1: aq. HCl; acetone / 0.5 h / 20 °C 3.1: acetic acid; pyrrolidine / benzene / 2 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 8 p. 2620 - 2626
反应条件
1.1: p-toluenesulfonic acid monohydrate / benzene / 3 h / Heating 2.1: Mg / tetrahydrofuran / 1 h / Heating 2.2: tetrahydrofuran / 2 h / Heating 3.1: aq. HCl; acetone / 0.5 h / 20 °C 4.1: acetic acid; pyrrolidine / benzene / 2 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 8 p. 2620 - 2626
反应条件
1: oxygen / water / 1.5 h / 79.84 °C / 750.08 Torr 2: air; Pd1–Au1 bimetal catalysts supported on basic layered double hydroxide / 1 h / 353 °C View Scheme
参考文献
Catalysis Communications, , vol. 47, p. 49 - 53
反应条件
aluminium trichloride in 1,2-dichloro-ethane
参考文献
Chemische Berichte, , vol. 110, p. 86 - 95
反应条件
1.1: sodium hydride / tetrahydrofuran / 0.58 h 1.2: tetrahydrofuran / 13.5 h 2.1: aq. HCl / 60 h / Heating 3.1: thionyl chloride / 17.5 h 4.1: urea; NaOEt / ethanol / 17 h / Heating 5.1: borane-tetrahydrofuran / tetrahydrofuran / 19 h / Heating View Scheme
参考文献
Shiba, Kazuhiro; Ogawa, Kazuma; Ishiwata, Kiichi; Yajima, Kazuyoshi; Mori, Hirofumi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 8 p. 2620 - 2626
