2-氯-2'-羟基苯甲酰苯胺合成路线 （共 6 条）
反应条件
1: ortho-chlorobenzoic acid With 1,1'-carbonyldiimidazole in tetrahydrofuran T=20°C; 0.166667 h; 2: 2-amino-phenol in tetrahydrofuran Heating; Further stages.;
参考文献
Kumar, Anil; Narasimhan, Balasubramanian; Kumar, Devinder
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 12 p. 4113 - 4124
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=25°C; 48 h;
参考文献
Klunder, Janice M.; Hargrave, Karl D.; West, MaryAnn; Cullen, Ernest; Pal, Kollol; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1887 - 1897
反应条件
potassium methanolate in various solvent(s) T=275°C;
参考文献
Klunder, Janice M.; Hargrave, Karl D.; West, MaryAnn; Cullen, Ernest; Pal, Kollol; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1887 - 1897
参考文献
Ramana, Devalla V.; Kantharaj, Ethirajulu
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 7 p. 1497 - 1502
反应条件
1: KOMe / various solvent(s) / 275 °C 2: NaH / dimethylformamide / Ambient temperature View Scheme
参考文献
Klunder, Janice M.; Hargrave, Karl D.; West, MaryAnn; Cullen, Ernest; Pal, Kollol; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1887 - 1897
反应条件
1: KOMe / various solvent(s) / 275 °C 2: NaH / dimethylformamide / Ambient temperature View Scheme
参考文献
Klunder, Janice M.; Hargrave, Karl D.; West, MaryAnn; Cullen, Ernest; Pal, Kollol; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1887 - 1897
