1-氯-3-(1-萘基氧基)丙-2-醇合成路线 （共 28 条）
反应条件
1: Et3N / 1 h / 80 - 90 °C 2: 100 percent / water, 10 percent aq. NaOH / 16 h / Ambient temperature View Scheme
参考文献
Bevinakatti; Banerji
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5372 - 5375
反应条件
1: Et3N / 1 h / 80 - 90 °C 2: 100 percent / water, 10 percent aq. NaOH / 16 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 18 p. 5372 - 5375
参考文献
Crowther,A.F.; Smith,L.H.
Journal of Medicinal Chemistry, 1968 , vol. 11, # 5 p. 1009 - 1013
反应条件
1: 92 percent / oxalyl chloride; DMSO / CH2Cl2 / 0.25 h / -70 °C
2: 87 percent / Yarrowia lipolytica; phosphate buffer; saccharose / benzene / 48 h / 28 °C / pH 7.0
View Scheme
参考文献
Bevinakatti; Banerji
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5372 - 5375
反应条件
triethylamine
T=80 - 90°C; 1 h;
参考文献
Bevinakatti; Banerji
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5372 - 5375
参考文献
Crowther,A.F.; Smith,L.H.
Journal of Medicinal Chemistry, 1968 , vol. 11, # 5 p. 1009 - 1013
反应条件
1: Pseudomonas sp. lipase / toluene / 5 h / 60 °C / Enzymatic reaction
2: LiOH / ethanol / 1 h / 20 °C
View Scheme
参考文献
Bevinakatti; Banerji
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5372 - 5375
反应条件
1: Et3N / 1 h / 80 - 90 °C
2: 20 percent aq. NaOH / propan-2-ol / Ambient temperature
View Scheme
参考文献
Bevinakatti; Banerji
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5372 - 5375
