1-氯-3-(1-萘基氧基)丙-2-醇合成路线 （共 28 条）
反应条件
1: With 1,8-diazabicyclo[5.4.0]undec-7-ene 0.333333 h; Heating; 2: With hydrogenchloride in dichloromethane T=5°C; 2 h;
参考文献
Kapoor; Anand; Koul; Chimni; Manhas; Raina; Parshad; Taneja; Qazi
Bioorganic Chemistry, 2003 , vol. 31, # 3 p. 259 - 269
反应条件
aluminum oxide; sodium tetrahydroborate in di-isopropyl ether T=40°C;
参考文献
Kamal, Ahmed; Sandbhor, Mahendra; Ali Shaik, Ahmad
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 17 p. 4581 - 4583
反应条件
hydrogenchloride in chloroform
参考文献
Bodor, Nicholas; ElKoussi, Alaaeldin; Kano, Masanobu; Nakamura, Toshio
Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 100 - 106
反应条件
1: 1.) morpholine, 2.) conc. HCl / 1.) reflux, 16 h, 2.) 15 min 2: conc. HCl / CHCl3 View Scheme
参考文献
Bodor, Nicholas; ElKoussi, Alaaeldin; Kano, Masanobu; Nakamura, Toshio
Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 100 - 106
反应条件
1: morpholine / 7.5 h / 110 - 120 °C 2: conc. HCl / CHCl3 View Scheme
参考文献
Bodor, Nicholas; ElKoussi, Alaaeldin; Kano, Masanobu; Nakamura, Toshio
Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 100 - 106
反应条件
sodium hydroxide in water 6 h; Heating;
参考文献
Bevinakatti; Banerji
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5372 - 5375
参考文献
Fourneau
Chem. Zentralbl., 1910 , vol. 81, # I p. 1134
参考文献
Marle
Journal of the Chemical Society, 1912 , vol. 101, p. 309
反应条件
1: Et3N / 1 h / 80 - 90 °C 2: 100 percent / water, 10 percent aq. NaOH / 16 h / Ambient temperature View Scheme
参考文献
Bevinakatti; Banerji
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5372 - 5375
反应条件
1: Et3N / 1 h / 80 - 90 °C 2: 100 percent / water, 10 percent aq. NaOH / 16 h / Ambient temperature View Scheme
参考文献
Bevinakatti; Banerji
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5372 - 5375
