1-(苯基乙炔基)-1-环己醇合成路线 （共 34 条）
反应条件
1: phenylacetylene With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran; hexane T=-78°C; 1 h; 2: cyclohexanone in tetrahydrofuran; hexane T=-78°C; 2 h; Further stages.;
参考文献
Yoshida, Masahiro; Hayashi, Maiko; Shishido, Kozo
Organic Letters, 2007 , vol. 9, # 9 p. 1643 - 1646
反应条件
2,6-dimethylpyridine; oxygen; copper(I) bromide in methanol T=45°C; Sonogashira coupling; P=760.051 Torr; 16 h;
参考文献
Yasukawa, Tomohiro; Miyamura, Hiroyuki; Kobayashi, Sh
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 18 p. 6208 - 6210
反应条件
palladium 10 on activated carbon; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in N,N-dimethyl acetamide T=110°C; Sonogashira coupling; 6 h; Inert atmosphere;
参考文献
Komaromi, Anna; Novak, Zoltan
Chemical Communications, 2008 , # 40 p. 4968 - 4970
反应条件
potassium tert-butylate in tetrahydrofuran T=20°C; 0.25 h;
参考文献
Organic Letters, , vol. 7, # 22 p. 4995 - 4998
反应条件
indium in dichloromethane 0.4 h; Heating;
参考文献
Auge, Jacques; Lubin-Germain, Nadege; Seghrouchni, Latifa
Tetrahedron Letters, 2002 , vol. 43, # 30 p. 5255 - 5256
反应条件
copper(l) iodide; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride T=80°C; Sonogashira coupling;
参考文献
Csekei, Marton; Novak, Zoltan; Kotschy, Andras
Tetrahedron, 2008 , vol. 64, # 6 p. 975 - 982
反应条件
potassium phosphate; bis(η3-allyl-μ-chloropalladium(II)); N,N,N′,N′-tetra(diphenylphosphinomethyl)pyridine-2,6-diamine in N,N-dimethyl acetamide; water T=100°C; Sonogashira Cross-Coupling; 20 h; Schlenk techniqueInert atmosphere;
参考文献
Zhou, Rong; Wang, Wei; Jiang, Zhi-Jie; Fu, Hai-Yan; Zheng, Xue-Li; Zhang, Chun-Chun; Chen, Hua; Li, Rui-Xiang
Catalysis Science and Technology, 2014 , vol. 4, # 3 p. 746 - 751
反应条件
potassium tert-butylate in tetrahydrofuran T=20°C;
参考文献
Organic Letters, , vol. 7, # 22 p. 4995 - 4998
反应条件
1: With tetrabutyl ammonium fluoride in tetrahydrofuran T=-78°C; alkynylation; 4 h; 2: With hydrogenchloride in methanol T=0°C; Hydrolysis;
参考文献
Shibato, Atsushi; Itagaki, Yoshifumi; Tayama, Eiji; Hokke, Yasutoshi; Asao, Naoki; Maruoka, Keiji
Tetrahedron, 2000 , vol. 56, # 30 p. 5373 - 5382
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; silver fluoride; sodium hydrogencarbonate in acetonitrile T=20°C; 3 h;
参考文献
Ye, Zhishi; Liu, Miaochang; Lin, Baoda; Wu, Huayue; Ding, Jinchang; Cheng, Jiang
Tetrahedron Letters, 2009 , vol. 50, # 5 p. 530 - 532
