n-butyllithium; tri-isopropoxy-borane in tetrahydrofuran; hexane T=-80°C; 2 h; Inert atmosphere;

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 - 20 °C 1.2: 24 h / -78 - 20 °C 2.1: tetrakis(triphenylphosphine) palladium(0); caesium carbonate / toluene / 0.67 h / 150 °C / Inert atmosphere; Microwave irradiation View Scheme